Automatized clustering and functional geometry of human parietofrontal networks for language, space, and number.

Détails

ID Serval
serval:BIB_CB65B42C1B47
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Automatized clustering and functional geometry of human parietofrontal networks for language, space, and number.
Périodique
Neuroimage
Auteur(s)
Simon O., Kherif F., Flandin G., Poline J.B., Rivière D., Mangin J.F., Le Bihan D., Dehaene S.
ISSN
1053-8119 (Print)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
2004
Volume
23
Numéro
3
Pages
1192-1202
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Human functional MRI studies frequently reveal the joint activation of parietal and of lateral and mesial frontal areas during various cognitive tasks. To analyze the geometrical organization of those networks, we used an automatized clustering algorithm that parcels out sets of areas based on their similar profile of task-related activations or deactivations. This algorithm allowed us to reanalyze published fMRI data (Simon, O., Mangin, J.F., Cohen, L., Le Bihan, D., Dehaene, S., 2002. Topographical layout of hand, eye, calculation, and language-related areas in the human parietal lobe. Neuron 33, 475-487) and to reproduce the previously observed geometrical organization of activations for saccades, attention, grasping, pointing, calculation, and language processing in the parietal lobe. Further, we show that this organization extends to lateral and mesial prefrontal regions. Relative to the parietal lobe, the prefrontal functional geometry is characterized by a partially symmetrical anteroposterior ordering of activations, a decreased representation of effector-specific tasks, and a greater emphasis on higher cognitive functions of attention, higher-order spatial representation, calculation, and language. Anatomically, our results in humans are closely homologous to the known connectivity of parietal and frontal regions in the macaque monkey.
Mots-clé
Animals, Attention/physiology, Cluster Analysis, Frontal Lobe/physiology, Functional Laterality/physiology, Hand Strength/physiology, Image Processing, Computer-Assisted, Language, Macaca, Nerve Net/physiology, Parietal Lobe/physiology, Saccades/physiology, Space Perception/physiology, Visual Perception/physiology
Pubmed
Web of science
Création de la notice
11/09/2011 14:35
Dernière modification de la notice
03/03/2018 21:26
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