Iridocyclectomy for neovascular glaucoma caused by proton-beam radiotherapy of pigmented ciliary adenocarcinoma.

Détails

ID Serval
serval:BIB_CB3C4F03DC99
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Iridocyclectomy for neovascular glaucoma caused by proton-beam radiotherapy of pigmented ciliary adenocarcinoma.
Périodique
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
Auteur(s)
Schalenbourg A., Coupland S., Kacperek A., Damato B.
ISSN
0721-832X
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
246
Numéro
10
Pages
1499-501
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
PURPOSE: To report neovascular glaucoma after proton-beam radiotherapy of an adenocarcinoma of the pigmented ciliary epithelium and its successful treatment by iridocyclectomy. PATIENT AND METHODS: A 65-year-old man developed neovascular glaucoma 10 months after proton-beam radiotherapy of a small pigmented iridociliary tumour with a clinical differential diagnosis of uveal melanoma or adenocarcinoma. The diagnosis of 'toxic tumour syndrome' was made, and iridocyclectomy performed. RESULTS: Histopathology and immunohistochemistry of the specimen diagnosed an adenocarcinoma of the pigmented ciliary epithelium, with the presence of mitoses suggesting residual viable tumour cells. The rubeosis regressed, with normalization of the intraocular pressure. Phacoemulsification for radiation-induced cataract restored VA to 6/9, which was better than that recorded at initial referral, the patient having longstanding cellophane maculopathy. CONCLUSIONS: Neovascular glaucoma after radiotherapy of a small, pigmented, ciliary body tumour raises the possibility of adenocarcinoma. This 'toxic tumour syndrome' may respond to iridocyclectomy of the irradiated tumour.
Mots-clé
Adenocarcinoma/pathology, Adenocarcinoma/radiotherapy, Aged, Ciliary Body/pathology, Ciliary Body/radiation effects, Glaucoma, Neovascular/etiology, Glaucoma, Neovascular/surgery, Humans, Intraocular Pressure, Iridectomy, Iris/surgery, Male, Phacoemulsification, Radiation Injuries/etiology, Radiation Injuries/surgery, Radiotherapy, Intensity-Modulated/adverse effects, Uveal Neoplasms/pathology, Uveal Neoplasms/radiotherapy, Visual Acuity
Pubmed
Web of science
Création de la notice
12/02/2010 12:45
Dernière modification de la notice
20/03/2018 13:22
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