Conduit artery compliance and distensibility are not necessarily reduced in hypertension.

Détails

ID Serval
serval:BIB_CA480485F946
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Conduit artery compliance and distensibility are not necessarily reduced in hypertension.
Périodique
Hypertension
Auteur(s)
Hayoz D., Rutschmann B., Perret F., Niederberger M., Tardy Y., Mooser V., Nussberger J., Waeber B., Brunner H.R.
ISSN
0194-911X
Statut éditorial
Publié
Date de publication
1992
Peer-reviewed
Oui
Volume
20
Numéro
1
Pages
1-6
Langue
anglais
Notes
Publication types: Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
Résumé
The goal of this study was to investigate whether the elastic behavior of conduit arteries of humans or rats is altered as a result of concomitant hypertension. Forearm arterial cross-sectional compliance-pressure curves were determined noninvasively by means of a high precision ultrasonic echo-tracking device coupled to a photoplethysmograph (Finapres system) allowing simultaneous arterial diameter and finger blood pressure monitoring. Seventeen newly diagnosed hypertensive patients with a humeral blood pressure of 163/103 +/- 4.4/2.2 mm Hg (mean +/- SEM) and 17 age- and sex-matched normotensive controls with a humeral blood pressure of 121/77 +/- 3.2/1.9 mm Hg were included in the study. Compliance-pressure curves were also established at the carotid artery of 16-week-old anesthetized spontaneously hypertensive rats (n = 14) as well as Wistar-Kyoto normotensive animals (n = 15) using the same echo-tracking device. In these animals, intra-arterial pressure was monitored in the contralateral carotid artery. Mean blood pressures averaged 197 +/- 4 and 140 +/- 3 mm Hg in the hypertensive and normotensive rats, respectively. Despite the considerable differences in blood pressure, the diameter-pressure and cross-sectional compliance-pressure and distensibility-pressure curves were not different when hypertensive patients or animals were compared with their respective controls. These results suggest that the elastic behavior of a medium size muscular artery (radial) in humans and of an elastic artery (carotid) in rats is not necessarily altered by an increase in blood pressure.
Mots-clé
Animals, Arteries, Blood Pressure, Elasticity, Humans, Hypertension, Male, Rats, Rats, Inbred SHR, Rats, Inbred WKY, Reference Values
Pubmed
Web of science
Création de la notice
17/01/2008 17:38
Dernière modification de la notice
03/03/2018 21:24
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