Circadian rhythm of plasma renin activity and plasma aldosterone in normal man and in renal allograft recipients
Details
Serval ID
serval:BIB_CA2F30E0E413
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Circadian rhythm of plasma renin activity and plasma aldosterone in normal man and in renal allograft recipients
Journal
Proceedings of the European Dialysis and Transplant Association
ISSN
0071-2736 (Print)
Publication state
Published
Issued date
1975
Volume
11
Pages
268-76
Notes
Comparative Study
Journal Article
Journal Article
Abstract
In normal supine man, a marked circadian rhythm was found in plasma renin activity (PRA) and in plasma aldosterone concentration, with highest levels in the morning and lowest in the evening. Short-term suppression of ACTH by dexamethasone did not eliminate the circadian variation of plasma aldosterone. In patients with a transplanted and thus denervated kidney, no such rhythm of PRA could be observed. From our data it is suggested that the normal circadian rhythm of PRA depends on intact renal innervation and is controlled by the central nervous system.
Keywords
Adrenocorticotropic Hormone/physiology
Adult
Aldosterone/*blood
*Circadian Rhythm
Dexamethasone/pharmacology
Diet
Female
Humans
Hydrocortisone/blood
Kidney/innervation/physiology
*Kidney Transplantation
Male
Middle Aged
Nephrectomy
Posture
Prednisone/therapeutic use
Renin/*blood
Sodium
Transplantation, Homologous
Pubmed
Create date
05/03/2008 17:41
Last modification date
20/08/2019 16:45