Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians.
Progress in Cardiovascular Diseases
Publication types: Journal Article ; Review
About 30 million people live above 2500 m in the Andean Mountains of South America. Among them are 5.5 million Aymaras, an ethnic group with its own language, living on the altiplano of Bolivia, Peru, and northern Chile at altitudes of up to 4400 m. In this high altitude region traces of human population go back for more than 2000 years with constant evolutionary pressure on its residents for genetic adaptation to high altitude. Aymaras as the assumed direct descendents of the ancient cultures living in this region were the focus of much research interest during the last decades and several distinctive adaptation patterns to life at high altitude have been described in this ethnic group. The aim of this article was to review the physiology and pathophysiology of circulatory adaptation and maladaptation to longtime altitude exposure in Aymaras and Caucasians.
Acclimatization, Altitude, Altitude Sickness/blood, Altitude Sickness/ethnology, Anoxia/blood, Anoxia/ethnology, Bolivia/ethnology, Cardiovascular Physiological Phenomena, Chile/ethnology, European Continental Ancestry Group, Evidence-Based Medicine, Humans, Hypertension, Pulmonary/ethnology, Indians, South American, Nitric Oxide/blood, Peru/ethnology, Polycythemia/ethnology, Pulmonary Circulation, Pulmonary Ventilation, South America/ethnology
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