Treatment of adult-onset Still's disease: a review

Détails

Ressource 1Télécharger: BIB_C8BCB433233B.P001.pdf (1002.46 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_C8BCB433233B
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Treatment of adult-onset Still's disease: a review
Périodique
Therapeutics and Clinical Risk Management
Auteur(s)
Jamilloux Y., Gerfaud-Valentin M., Henry T., Seve P.
ISSN
1178-203X
Statut éditorial
Publié
Date de publication
2015
Volume
110
Pages
33-43
Langue
anglais
Résumé
Adult-onset Still's disease (AOSD) is a rare inflammatory disorder that has been recently classified as a polygenic autoinflammatory disorder. The former classification, based on the disease course, seems to be quite dated. Indeed, there is accumulating evidence that AOSD can be divided into two distinct phenotypes based on cytokine profile, clinical presentation, and outcome, ie, a "systemic" pattern and an "articular" pattern. The first part of this review deals with the treatments that are currently available for AOSD. We then present the different strategies based on the characteristics of the disease according to clinical presentation. To do so, we focus on the two subsets of the disease. Finally, we discuss the management of life-threatening complications of AOSD, along with the therapeutic options during pregnancy.
Mots-clé
adult-onset Still's disease, treatment, anakinra, tocilizumab, canakinumab
Web of science
Création de la notice
15/01/2015 12:20
Dernière modification de la notice
03/03/2018 21:21
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