Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Combined small-cell and transitional cell carcinoma of the renal pelvis. A light microscopic, immunohistochemical, and ultrastructural study of a case with literature review.
Archives of Pathology & Laboratory Medicine
Publication types: Case Reports ; Journal Article ; Review
Primary small-cell carcinomas of the kidney are rare, locally aggressive, and rapidly fatal neoplasms in elderly people. We report an example of combined small-cell and transitional cell carcinoma of the renal pelvis in a 71-year-old woman who had a history of heavy smoking. The cells that pertained to the small-cell component were morphologically mostly of an intermediate type. Immunohistochemically, they reacted with synaptophysin, carcinoembryonic antigen, and epithelial markers (Lu-5, EAB902, EAB903, and cytokeratin 19), and they contained scanty neurosecretory granules at the ultrastructural level. We review the literature on small-cell carcinoma of the kidney and renal pelvis, and we discuss the histogenesis of such a tumor.
Aged, Carcinoma, Small Cell/chemistry, Carcinoma, Small Cell/pathology, Carcinoma, Transitional Cell/chemistry, Carcinoma, Transitional Cell/pathology, Female, Humans, Immunohistochemistry, Kidney Neoplasms/chemistry, Kidney Neoplasms/pathology, Kidney Pelvis, Neoplasms, Multiple Primary/chemistry, Neoplasms, Multiple Primary/pathology
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