Methadone treatments in a Swiss Region, 2001-2008: a registry-based analysis.

Détails

Ressource 1Télécharger: BIB_C87E97C2B6DB.P001.pdf (520.82 [Ko])
Etat: Serval
Version: de l'auteur
ID Serval
serval:BIB_C87E97C2B6DB
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Methadone treatments in a Swiss Region, 2001-2008: a registry-based analysis.
Périodique
BMC Psychiatry
Auteur(s)
Huissoud Thérèse, Rousson Valentin, Dubois-Arber Françoise
ISSN
1471-244X (Electronic)
ISSN-L
1471-244X
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
12
Numéro
1
Pages
art. 238 [11 p.]
Langue
anglais
Notes
Publication types: JOURNAL ARTICLE
Résumé
ABSTRACT: BACKGROUND: To determine, in a region of Switzerland, the duration of retention in opioid substitution treatments with methadone (OSTM), duration of treatment interruptions, probability of re-entry to treatment after a treatment interruption, and associated factors. METHODS: A secondary analysis of registry-based data was performed with patients (n = 2880) registered in the methadone treatment register database of the Public Health Service of the canton of Vaud between January 1, 2001 and June 30, 2008. Survival analysis and multivariate analysis was conducted. RESULTS: The probability of remaining on treatment was 69% at 1 year and 45% at 3 years (n =1666). One-third of patients remained on treatment beyond 5 years. The estimated hazard of leaving treatment was increased by a ratio of 1.31 in the case of a first treatment (P = 0.001), 1.83 for those without a fixed home (P < 0.001), and 1.29 for those younger than 30 years old (P < 0.001). The probability of having begun a new treatment after a first interruption was 21% at one year, 38% at 3 years, and 43% at 5 years (n = 1581). Factors at the interruption of treatment associated with a higher probability of re-entering were: interruption not due to methadone withdrawal, bad physical health, and higher methadone dose. CONCLUSIONS: OSTM are long-term (maintenance) treatments in Switzerland. Younger age, bad living conditions at entry, and first treatment are predictors of lower retention. Approximately one-half of patients who interrupt treatment will re-enter treatment within 5 years.
Pubmed
Web of science
Open Access
Oui
Création de la notice
03/01/2013 13:58
Dernière modification de la notice
09/05/2019 1:09
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