On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA)

Details

Serval ID
serval:BIB_C84D5C4EEC24
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA)
Journal
Magnetic Resonance in Medicine
Author(s)
Vonken E.J., Korosoglou F., Yu J., Schar M., Weissleder R., Stuber M.
ISSN
1522-2594
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
62
Number
2
Pages
314-324
Language
english
Notes
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Abstract
The susceptibility of blood changes after administration of a paramagnetic contrast agent that shortens T(1). Concomitantly, the resonance frequency of the blood vessels shifts in a geometry-dependent way. This frequency change may be exploited for incremental contrast generation by applying a frequency-selective saturation prepulse prior to the imaging sequence. The dual origin of vascular enhancement depending first on off-resonance and second on T(1) lowering was investigated in vitro, together with the geometry dependence of the signal at 3T. First results obtained in an in vivo rabbit model are presented.
Pubmed
Web of science
Open Access
Yes
Create date
02/03/2010 16:04
Last modification date
20/08/2019 15:43
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