Value of positron emission tomography in full-thickness chest wall resections for malignancies.

Détails

ID Serval
serval:BIB_C8095A3EF5BA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Value of positron emission tomography in full-thickness chest wall resections for malignancies.
Périodique
Interactive Cardiovascular and Thoracic Surgery
Auteur(s)
Petermann D., Allenbach G., Schmidt S., Letovanec I., Christodoulou M., Bischof Delaloye A., Ris H.B., Prior J.O.
ISSN
1569-9285[electronic]
Statut éditorial
Publié
Date de publication
2009
Volume
9
Numéro
3
Pages
406-410
Langue
anglais
Résumé
Preoperative imaging for resection of chest wall malignancies is generally performed by computed tomography (CT). We evaluated the role of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in planning full-thickness chest wall resections for malignancies. We retrospectively included 18 consecutive patients operated from 2004 to 2006 at our institution. Tumor extent was measured by CT and PET, using the two largest perpendicular tumor extensions in the chest wall plane to compute the tumor surface assuming an elliptical shape. Imaging measurements were compared to histopathology assessment of tumor borders. CT assessment consistently overestimated the tumor size as compared to PET (+64% vs. +1%, P<0.001). Moreover, PET was significantly better than CT at defining the size of lesions >24 cm(2) corresponding to a mean diameter >5.5 cm or an ellipse of >4 cm x 7.6 cm (positive predictive value 80% vs. 44% and specificity 93% vs. 64%, respectively). Metabolic PET imaging was superior to CT for defining the extent of chest wall tumors, particularly for tumors with a diameter >5.5 cm. PET can complement CT in planning full-thickness chest wall resection for malignancies, but its true value remains to be determined in larger, prospective studies.
Mots-clé
Adult, Aged, Female, Fluorodeoxyglucose F18/diagnostic use, Humans, Male, Middle Aged, Neoplasm Invasiveness, Positron-Emission Tomography, Predictive Value of Tests, Radiopharmaceuticals/diagnostic use, Retrospective Studies, Thoracic Neoplasms/radiography, Thoracic Neoplasms/radionuclide imaging, Thoracic Surgical Procedures, Thoracic Wall/radiography, Thoracic Wall/radionuclide imaging, Tomography, X-Ray Computed
Pubmed
Open Access
Oui
Création de la notice
25/08/2009 10:40
Dernière modification de la notice
20/08/2019 16:43
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