Symbiotic cooperation in the biosynthesis of a phytotoxin.

Détails

ID Serval
serval:BIB_C7316DBA5098
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Symbiotic cooperation in the biosynthesis of a phytotoxin.
Périodique
Angewandte Chemie
Auteur(s)
Scherlach K., Busch B., Lackner G., Paszkowski U., Hertweck C.
ISSN
1521-3773 (Electronic)
ISSN-L
1433-7851
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
51
Numéro
38
Pages
9615-9618
Langue
anglais
Résumé
Division of labor: A combination of genetic, microbial, and chemical analyses solved the riddle of the dual epoxidation in the biosynthesis of rhizoxin, the causative agent of rice seedling blight. Bacterial endosymbionts of Rhizopus microsporus mediate the first epoxidation by a dedicated cytochrome P450 monooxygenase. The second oxirane ring is introduced by the fungal host and results in a substantially increased potency of the phytotoxin.
Mots-clé
Chromatography, High Pressure Liquid, Macrolides/chemistry, Macrolides/metabolism, Molecular Structure, Rhizopus/chemistry
Pubmed
Web of science
Création de la notice
06/10/2016 15:49
Dernière modification de la notice
03/03/2018 21:19
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