A rare case of ectopic adrenocorticotropic hormone syndrome caused by a metastatic neuroendocrine tumor of the pancreas detected by 68Ga-DOTANOC and 18F-FDG PET/CT.
Details
Serval ID
serval:BIB_C72701A5958F
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
A rare case of ectopic adrenocorticotropic hormone syndrome caused by a metastatic neuroendocrine tumor of the pancreas detected by 68Ga-DOTANOC and 18F-FDG PET/CT.
Journal
Clinical nuclear medicine
ISSN
1536-0229 (Electronic)
ISSN-L
0363-9762
Publication state
Published
Issued date
07/2013
Peer-reviewed
Oui
Volume
38
Number
7
Pages
e306-8
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
We report a rare case of ectopic adrenocorticotropic hormone (ACTH) syndrome caused by a metastatic neuroendocrine tumor (NET) of the pancreas detected by PET/CT using different tracers. A 43-year-old female patient with Cushing syndrome (CS) by suspected ectopic ACTH secretion underwent a 68Ga-DOTANOC and a 18F-FDG PET/CT. Both these functional imaging techniques revealed increased tracer uptake in a pancreatic mass and multiple liver metastases. Histology showed the presence of a mildly differentiated pancreatic NET. 68Ga-DOTANOC PET/CT may be a useful functional imaging method, complementary to 18F-FDG PET/CT, in detecting ACTH-secreting pancreatic NETs.
Keywords
ACTH Syndrome, Ectopic/diagnostic imaging, ACTH Syndrome, Ectopic/etiology, Adult, Cell Differentiation, Female, Fluorodeoxyglucose F18, Glucose/metabolism, Humans, Multimodal Imaging, Neoplasm Metastasis, Neuroendocrine Tumors/complications, Neuroendocrine Tumors/diagnostic imaging, Neuroendocrine Tumors/pathology, Organometallic Compounds, Pancreatic Neoplasms/complications, Pancreatic Neoplasms/diagnostic imaging, Pancreatic Neoplasms/pathology, Positron-Emission Tomography, Tomography, X-Ray Computed
Pubmed
Web of science
Create date
20/08/2017 21:01
Last modification date
20/08/2019 16:42
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