CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT.

Détails

Ressource 1Télécharger: BIB_C66A4042E3BE.P001.pdf (632.82 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_C66A4042E3BE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
CT attenuation values of blood and myocardium: rationale for accurate coronary artery calcifications detection with multi-detector CT.
Périodique
Plos One
Auteur(s)
Qanadli S.D., Jouannic A.M., Dehmeshki J., Lu T.L.
ISSN
1932-6203 (Electronic)
ISSN-L
1932-6203
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
10
Numéro
4
Pages
e0124175
Langue
anglais
Notes
Publication types: Journal Article Publication Status: epublish
Résumé
OBJECTIVES: To determine inter-session and intra/inter-individual variations of the attenuations of aortic blood/myocardium with MDCT in the context of calcium scoring. To evaluate whether these variations are dependent on patients' characteristics.
METHODS: Fifty-four volunteers were evaluated with calcium scoring non-enhanced CT. We measured attenuations (inter-individual variation) and standard deviations (SD, intra-individual variation) of the blood in the ascending aorta and of the myocardium of left ventricle. Every volunteer was examined twice to study the inter-session variation. The fat pad thickness at the sternum and noise (SD of air) were measured too. These values were correlated with the measured aortic/ventricular attenuations and their SDs (Pearson). Historically fixed thresholds (90 and 130 HU) were tested against different models based on attenuations of blood/ventricle.
RESULTS: The mean attenuation was 46 HU (range, 17-84 HU) with mean SD 23 HU for the blood, and 39 HU (10-82 HU) with mean SD 18 HU for the myocardium. The attenuation/SD of the blood were significantly higher than those of the myocardium (p < 0.01). The inter-session variation was not significant. There was a poor correlation between SD of aortic blood/ventricle with fat thickness/noise. Based on existing models, 90 HU threshold offers a confidence interval of approximately 95% and 130 HU more than 99%.
CONCLUSIONS: Historical thresholds offer high confidence intervals for exclusion of aortic blood/myocardium and by the way for detecting calcifications. Nevertheless, considering the large variations of blood/myocardium CT values and the influence of patient's characteristics, a better approach might be an adaptive threshold.
Mots-clé
Aged, Calcinosis/diagnosis, Calcinosis/radiography, Coronary Vessels/radiography, Female, Heart/radiography, Humans, Male, Middle Aged, Tomography, X-Ray Computed
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/04/2015 18:08
Dernière modification de la notice
20/08/2019 16:41
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