Metabolomics as a Tool to Understand Pathophysiological Processes

Détails

ID Serval
serval:BIB_C58D083EA586
Type
Partie de livre
Sous-type
Chapitre: chapitre ou section
Collection
Publications
Titre
Metabolomics as a Tool to Understand Pathophysiological Processes
Titre du livre
Methods in Molecular Biology
Auteur(s)
Ivanisevic Julijana, Thomas Aurelien
Editeur
Springer New York
ISBN
9781493975914
9781493975921
ISSN
1064-3745
1940-6029
ISSN-L
1064-3745
Statut éditorial
Publié
Date de publication
2018
Peer-reviewed
Oui
Volume
1730
Série
Methods in Molecular Biology
Numéro de chapitre
1
Pages
3-28
Langue
anglais
Résumé
Multiple diseases have a strong metabolic component, and metabolomics as a powerful phenotyping technology, in combination with orthogonal biological and clinical approaches, will undoubtedly play a determinant role in accelerating the understanding of mechanisms that underlie these complex diseases determined by a set of genetic, lifestyle, and environmental exposure factors. Here, we provide several examples of valuable findings from metabolomics-led studies in diabetes and obesity metabolism, neurodegenerative disorders, and cancer metabolism and offer a longer term vision toward personalized approach to medicine, from population-based studies to pharmacometabolomics.

Mots-clé
Liquid chromatography–mass spectrometry Clinical chemistry Personalized health care Precision medicine Disease markers Gas chromatography–mass spectrometry
Pubmed
Web of science
Création de la notice
27/01/2018 12:16
Dernière modification de la notice
15/01/2019 7:26
Données d'usage