Structural motifs of biomolecules.

Détails

ID Serval
serval:BIB_C533F9D0505C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Structural motifs of biomolecules.
Périodique
Proceedings of the National Academy of Sciences of the United States of America
Auteur(s)
Banavar J.R., Hoang T.X., Maddocks J.H., Maritan A., Poletto C., Stasiak A., Trovato A.
ISSN
0027-8424
Statut éditorial
Publié
Date de publication
10/2007
Peer-reviewed
Oui
Volume
104
Numéro
44
Pages
17283-17286
Langue
anglais
Résumé
Biomolecular structures are assemblies of emergent anisotropic building modules such as uniaxial helices or biaxial strands. We provide an approach to understanding a marginally compact phase of matter that is occupied by proteins and DNA. This phase, which is in some respects analogous to the liquid crystal phase for chain molecules, stabilizes a range of shapes that can be obtained by sequence-independent interactions occurring intra- and intermolecularly between polymeric molecules. We present a singularity-free self-interaction for a tube in the continuum limit and show that this results in the tube being positioned in the marginally compact phase. Our work provides a unified framework for understanding the building blocks of biomolecules.
Mots-clé
DNA/chemistry, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Protein Conformation, Proteins/chemistry
Pubmed
Web of science
Open Access
Oui
Création de la notice
24/01/2008 11:36
Dernière modification de la notice
09/05/2019 0:59
Données d'usage