IRE1 gives weight to obesity-associated inflammation.

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Serval ID
serval:BIB_C4E37AD3DCD4
Type
Article: article from journal or magazin.
Publication sub-type
Editorial
Collection
Publications
Institution
UNIL/CHUV
Title
IRE1 gives weight to obesity-associated inflammation.
Journal
Nature immunology
Author(s)
Bujisic B., Martinon F.
ISSN
1529-2916 (Electronic)
ISSN-L
1529-2908
Publication state
Published
Issued date
18/04/2017
Peer-reviewed
Oui
Volume
18
Number
5
Pages
479-480
Language
english
Notes
Publication types: Journal Article ; Comment
Publication Status: ppublish
Abstract
IRE1 alpha is a stress sensor that is activated by a high-fat diet. In adipose-tissue macrophages, it serves as a major switch toward pro-inflammatory M1 polarization and thereby contributes to obesity and associated diseases.
Keywords
Endoribonucleases, Humans, Inflammation, Obesity, Protein-Serine-Threonine Kinases
OAI-PMH
oai:serval.unil.ch:BIB_C4E37AD3DCD4
DOI
10.1038/ni.3725
Pubmed
28418390
Web of science
000399378700002
Create date
19/04/2017 15:11
Last modification date
20/08/2019 16:40
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