Methodologies for <i>in vitro</i> and <i>in vivo</i> evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Détails

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Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_C3011A74E6CB
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Methodologies for <i>in vitro</i> and <i>in vivo</i> evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.
Périodique
Microbial cell
Auteur(s)
Van Dijck P., Sjollema J., Cammue B.P., Lagrou K., Berman J., d'Enfert C., Andes D.R., Arendrup M.C., Brakhage A.A., Calderone R., Cantón E., Coenye T., Cos P., Cowen L.E., Edgerton M., Espinel-Ingroff A., Filler S.G., Ghannoum M., Gow NAR, Haas H., Jabra-Rizk M.A., Johnson E.M., Lockhart S.R., Lopez-Ribot J.L., Maertens J., Munro C.A., Nett J.E., Nobile C.J., Pfaller M.A., Ramage G., Sanglard D., Sanguinetti M., Spriet I., Verweij P.E., Warris A., Wauters J., Yeaman M.R., Zaat SAJ, Thevissen K.
ISSN
2311-2638 (Print)
ISSN-L
2311-2638
Statut éditorial
Publié
Date de publication
14/06/2018
Peer-reviewed
Oui
Volume
5
Numéro
7
Pages
300-326
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Résumé
Unlike superficial fungal infections of the skin and nails, which are the most common fungal diseases in humans, invasive fungal infections carry high morbidity and mortality, particularly those associated with biofilm formation on indwelling medical devices. Therapeutic management of these complex diseases is often complicated by the rise in resistance to the commonly used antifungal agents. Therefore, the availability of accurate susceptibility testing methods for determining antifungal resistance, as well as discovery of novel antifungal and antibiofilm agents, are key priorities in medical mycology research. To direct advancements in this field, here we present an overview of the methods currently available for determining (i) the susceptibility or resistance of fungal isolates or biofilms to antifungal or antibiofilm compounds and compound combinations; (ii) the <i>in vivo</i> efficacy of antifungal and antibiofilm compounds and compound combinations; and (iii) the <i>in vitro</i> and <i>in vivo</i> performance of anti-infective coatings and materials to prevent fungal biofilm-based infections.
Mots-clé
antibiofilm material coating, antifungal susceptibility testing, biofilm eradication, biofilm inhibition, in vivo models
Pubmed
Web of science
Open Access
Oui
Création de la notice
18/07/2018 15:28
Dernière modification de la notice
20/08/2019 16:38
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