Association between melanism, physiology and behaviour: a role for the melanocortin system.

Détails

Ressource 1Télécharger: BIB_C28BA5538A77.P001.pdf (867.16 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_C28BA5538A77
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Association between melanism, physiology and behaviour: a role for the melanocortin system.
Périodique
European Journal of Pharmacology
Auteur(s)
Roulin A., Ducrest A.L.
ISSN
1879-0712 (Electronic)
ISSN-L
0014-2999
Statut éditorial
Publié
Date de publication
2011
Peer-reviewed
Oui
Volume
660
Numéro
1
Pages
226-233
Langue
anglais
Résumé
The melanocortin system is implicated in the expression of many phenotypic traits. Activation of the melanocortin MC(1) receptor by melanocortin hormones induces the production of brown/black eumelanic pigments, while activation of the four other melanocortin receptors affects other physiological and behavioural functions including stress response, energy homeostasis, anti-inflammatory and sexual activity, aggressiveness and resistance to oxidative stress. We recently proposed the hypothesis that some melanocortin-physiological and -behavioural traits are correlated within individuals. This hypothesis predicts that the degree of eumelanin production may, in some cases, be associated with the regulation of glucocorticoids, immunity, resistance to oxidative stress, energy homeostasis, sexual activity, and aggressiveness. A review of the zoological literature and detailed experimental studies in a free-living population of barn owls (Tyto alba) showed that indeed melanic coloration is often correlated with the predicted physiological and behavioural traits. Support for predictions of the hypothesis that covariations between coloration and other phenotypic traits stem from pleiotropic effects of the melanocortin system raises a number of theoretical and empirical issues from evolutionary and pharmacological point of views.
Mots-clé
Animals, Behavior/drug effects, Humans, Melanocortins/genetics, Melanocortins/metabolism, Melanosis/genetics, Melanosis/metabolism, Phenotype, Physiological Processes/drug effects, Strigiformes/genetics, Strigiformes/metabolism
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/11/2010 18:32
Dernière modification de la notice
09/05/2019 0:50
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