Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome

Détails

ID Serval
serval:BIB_C259E3420BF0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomised controlled trial in patients with failed back surgery syndrome
Périodique
Pain
Auteur(s)
Kumar  K., Taylor  R. S., Jacques  L., Eldabe  S., Meglio  M., Molet  J., Thomson  S., O'Callaghan  J., Eisenberg  E., Milbouw  G., Buchser  E., Fortini  G., Richardson  J., North  R. B.
ISSN
1872-6623 (Electronic)
Statut éditorial
Publié
Date de publication
11/2007
Volume
132
Numéro
1-2
Pages
179-88
Notes
Journal Article --- Old month value: Nov
Résumé
Patients with neuropathic pain secondary to failed back surgery syndrome (FBSS) typically experience persistent pain, disability, and reduced quality of life. We hypothesised that spinal cord stimulation (SCS) is an effective therapy in addition to conventional medical management (CMM) in this patient population. We randomised 100 FBSS patients with predominant leg pain of neuropathic radicular origin to receive spinal cord stimulation plus conventional medical management (SCS group) or conventional medical management alone (CMM group) for at least 6 months. The primary outcome was the proportion of patients achieving 50% or more pain relief in the legs. Secondary outcomes were improvement in back and leg pain, health-related quality of life, functional capacity, use of pain medication and non-drug pain treatment, level of patient satisfaction, and incidence of complications and adverse effects. Crossover after the 6-months visit was permitted, and all patients were followed up to 1 year. In the intention-to-treat analysis at 6 months, 24 SCS patients (48%) and 4 CMM patients (9%) (p<0.001) achieved the primary outcome. Compared with the CMM group, the SCS group experienced improved leg and back pain relief, quality of life, and functional capacity, as well as greater treatment satisfaction (p<or=0.05 for all comparisons). Between 6 and 12 months, 5 SCS patients crossed to CMM, and 32 CMM patients crossed to SCS. At 12 months, 27 SCS patients (32%) had experienced device-related complications. In selected patients with FBSS, SCS provides better pain relief and improves health-related quality of life and functional capacity compared with CMM alone.
Pubmed
Web of science
Création de la notice
28/01/2008 11:41
Dernière modification de la notice
20/08/2019 16:37
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