Distinct modes of functional connectivity induced by movie-watching.

Détails

ID Serval
serval:BIB_C2545CAD2ED1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Distinct modes of functional connectivity induced by movie-watching.
Périodique
NeuroImage
Auteur(s)
Demirtaş M., Ponce-Alvarez A., Gilson M., Hagmann P., Mantini D., Betti V., Romani G.L., Friston K., Corbetta M., Deco G.
ISSN
1095-9572 (Electronic)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
01/01/2019
Peer-reviewed
Oui
Volume
184
Pages
335-348
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
A fundamental question in systems neuroscience is how endogenous neuronal activity self-organizes during particular brain states. Recent neuroimaging studies have demonstrated systematic relationships between resting-state and task-induced functional connectivity (FC). In particular, continuous task studies, such as movie watching, speak to alterations in coupling among cortical regions and enhanced fluctuations in FC compared to the resting-state. This suggests that FC may reflect systematic and large-scale reorganization of functionally integrated responses while subjects are watching movies. In this study, we characterized fluctuations in FC during resting-state and movie-watching conditions. We found that the FC patterns induced systematically by movie-watching can be explained with a single principal component. These condition-specific FC fluctuations overlapped with inter-subject synchronization patterns in occipital and temporal brain regions. However, unlike inter-subject synchronization, condition-specific FC patterns were characterized by increased correlations within frontal brain regions and reduced correlations between frontal-parietal brain regions. We investigated these condition-specific functional variations as a shorter time scale, using time-resolved FC. The time-resolved FC showed condition-specificity over time; notably when subjects watched both the same and different movies. To explain self-organisation of global FC through the alterations in local dynamics, we used a large-scale computational model. We found that condition-specific reorganization of FC could be explained by local changes that engendered changes in FC among higher-order association regions, mainly in frontal and parietal cortices.
Mots-clé
Adult, Brain/physiology, Brain Mapping/methods, Female, Humans, Image Processing, Computer-Assisted/methods, Magnetic Resonance Imaging, Male, Motion Pictures, Nerve Net/physiology, Principal Component Analysis, Young Adult
Pubmed
Web of science
Création de la notice
29/10/2018 11:14
Dernière modification de la notice
20/08/2019 16:37
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