Article: article from journal or magazin.
Microcontroller-driven fluid-injection system for atomic force microscopy.
Review of Scientific Instruments
We present a programmable microcontroller-driven injection system for the exchange of imaging medium during atomic force microscopy. Using this low-noise system, high-resolution imaging can be performed during this process of injection without disturbance. This latter circumstance was exemplified by the online imaging of conformational changes in DNA molecules during the injection of anticancer drug into the fluid chamber.
Air, Antibiotics, Antineoplastic/chemistry, DNA, Bacterial/chemistry, DNA, Superhelical/chemistry, Daunorubicin/chemistry, Electromagnetic Fields/adverse effects, Equipment Design, Escherichia coli, Microscopy, Atomic Force/instrumentation, Microtechnology/instrumentation, Nucleic Acid Conformation, Plasmids/chemistry
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