Poor oral hygiene enhances gingival overgrowth caused by calcineurin inhibitors.

Details

Serval ID
serval:BIB_C20D6720D6FB
Type
Article: article from journal or magazin.
Collection
Publications
Title
Poor oral hygiene enhances gingival overgrowth caused by calcineurin inhibitors.
Journal
Journal of Clinical Pharmacy and Therapeutics
Author(s)
Reali L., Zuliani E., Gabutti L., Schönholzer C., Marone C.
ISSN
1365-2710 (Electronic)
ISSN-L
0269-4727
Publication state
Published
Issued date
2009
Volume
34
Number
3
Pages
255-260
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Publication Status: ppublish
Abstract
AIM: To estimate the prevalence of gingival overgrowth in kidney allograft recipients in southern Switzerland and to determine the factors associated with it. We hypothesized that poor oral hygiene was a risk factor.
METHODS: We assessed the level of oral hygiene among renal transplant patients and determined whether a good level of information and regular dental checkups in addition to good oral hygiene could prevent gingival hyperplasia. Seventy-six adults who had undergone kidney transplantation were examined. The level of oral hygiene, gender, age, time elapsed from transplantation, medication and dose were recorded.
RESULTS: In general the level of oral hygiene was average. We found a significant association between the severity of gingival overgrowth and the level of oral hygiene. No statistical relationship between gingival hyperplasia and the other recorded variables was detected. Patients on tacrolimus had a tendency to have less gingival hyperplasia. Patient education, along with regular dental checkups and a good level of oral hygiene, should prevent gingival hyperplasia or maintain it at an acceptable level.
CONCLUSION: Intensive motivation of patients to maintain good oral hygiene is necessary to reduce the incidence of gingival hyperplasia.
Keywords
Adult, Aged, Calcineurin/antagonists & inhibitors, Cross-Sectional Studies, Cyclosporine/adverse effects, Cyclosporine/pharmacology, Female, Gingival Hyperplasia/chemically induced, Gingival Hyperplasia/epidemiology, Humans, Immunosuppressive Agents/adverse effects, Immunosuppressive Agents/pharmacology, Kidney Transplantation, Male, Middle Aged, Oral Hygiene, Patient Education as Topic, Risk Factors, Severity of Illness Index, Switzerland/epidemiology, Tacrolimus/adverse effects, Tacrolimus/pharmacology
Pubmed
Create date
24/07/2013 10:28
Last modification date
16/04/2020 6:26
Usage data