Etat de mal épiteptique et neurodégénérescence: entre circuits et cercles vicieux [Status epilepticus and neuronal degeneration: of circuitries and vicious circles]

Détails

ID Serval
serval:BIB_C1EE152FA8A6
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Etat de mal épiteptique et neurodégénérescence: entre circuits et cercles vicieux [Status epilepticus and neuronal degeneration: of circuitries and vicious circles]
Périodique
Revue Médicale Suisse
Auteur(s)
Rossetti A.O., Perrig S., Landis T., Despland P.A., Seeck M.
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
05/2006
Volume
2
Numéro
64
Pages
1185-1191
Langue
français
Notes
English Abstract Journal Article Review --- Old month value: May 3
Résumé
The relationship between status epilepticus (SE) and neuronal degeneration is quite complex and difficult to investigate. Animal studies suggest that SE induces a progressive neuronal death; however, clinical observations on humans are less uniform: generalized SE may precede the development of hippocampal sclerosis, but other forms (such as simple-partial or complex-partial) seem less ominous. On the other side, SE can be encountered in many patients with neurodegenerative disorders, particularly those with severe forms. It is thus likely that SE represents a sign, rather than an aetiology, of clinical gravity. Therefore, while it is ancillary to treat rapidly any SE form, the therapeutic approach, especially the use of aggressive treatments, should be tailored according to the underlying medical conditions.
Mots-clé
Animals, Humans, Neurodegenerative Diseases, Status Epilepticus
Pubmed
Création de la notice
25/01/2008 12:40
Dernière modification de la notice
03/03/2018 21:08
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