Les calcifications pulmonaires métastatiques [Pulmonary metastatic calcification].

Détails

ID Serval
serval:BIB_C0D2FC909A84
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Les calcifications pulmonaires métastatiques [Pulmonary metastatic calcification].
Périodique
Revue des Maladies Respiratoires
Auteur(s)
Pasquier M., Schaller M.D., Abdou M., Eckert P.
ISSN
1776-2588 (Electronic)
ISSN-L
0761-8425
Statut éditorial
Publié
Date de publication
2012
Peer-reviewed
Oui
Volume
29
Numéro
6
Pages
775-784
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Résumé
INTRODUCTION: The lung is the organ most frequently involved by metastatic calcification. This condition is probably under-diagnosed, the patients usually being asymptomatic. This article summarizes the current knowledge concerning pulmonary metastatic calcification.
BACKGROUND: The pathogenesis of pulmonary metastatic calcification is not well known, but it involves phosphate-calcium balance, renal function and pH. The most frequently encountered aetiologies are hyperparathyroidism, neoplastic bony lesions, and renal failure. The definitive diagnosis is achieved by histology, radiological examinations being insensitive. The clinical manifestations are various and can include a pulmonary restrictive syndrome, diffusion abnormalities, hypoxaemia and respiratory failure. The latter can be severe and influence the prognosis adversely: 19 cases of fatal pulmonary metastatic calcification have been reported. The treatment is aetiological and symptomatic.
VIEWPOINT: The prognostic factors for a poor outcome of this potentially lethal condition remain to be determined. The management of asymptomatic patients is also uncertain.
CONCLUSIONS: Pulmonary metastatic calcification is a rare condition of complex pathogenesis. The clinical manifestations are varied, ranging from asymptomatic to severe, even fatal.
Pubmed
Web of science
Création de la notice
27/08/2012 18:39
Dernière modification de la notice
18/06/2018 8:32
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