Candidoses invasives en reanimation. [Invasive candidiasis in critically ill patients]

Détails

ID Serval
serval:BIB_C0C1228408B7
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Candidoses invasives en reanimation. [Invasive candidiasis in critically ill patients]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur(s)
Eggimann  P., Pittet  D.
ISSN
0036-7672 (Print)
Statut éditorial
Publié
Date de publication
10/2000
Volume
130
Numéro
42
Pages
1525-37
Notes
English Abstract
Journal Article
Review --- Old month value: Oct 21
Résumé
Invasive candidiasis is rare in the general population (about 8 episodes/100,000/year), but has a higher incidence in hospitalised patients (0.5/1000 admissions). It complicates about 10 per 1000 admissions in critical care, where it represents 10-15% of all nosocomial infections. Candidiasis remains difficult to diagnose and its mortality is as high as those of septic shock (40-60%). A better knowledge of the pathophysiology of the disease and the availability of triazole compounds that are less toxic than amphotericin have given rise to the concept of early empirical or preemptive treatment. Prophylaxis of invasive candidiasis, which is very effective, is based on risk factor identification. However, prophylaxis must be restricted to carefully selected groups of patients, to avoid the emergence of resistant strains and a shift in the distribution of pathogens from albicans to non-albicans strains under the pressure of antifungal agents.
Mots-clé
Antifungal Agents/*therapeutic use Candidiasis/drug therapy/epidemiology/*prevention & control *Critical Illness Cross Infection/drug therapy/prevention & control Humans Incidence
Pubmed
Web of science
Création de la notice
24/01/2008 17:57
Dernière modification de la notice
03/03/2018 21:06
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