Whole-cell living biosensors--are they ready for environmental application?

Détails

ID Serval
serval:BIB_C07260FF8F30
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Whole-cell living biosensors--are they ready for environmental application?
Périodique
Applied Microbiology and Biotechnology
Auteur(s)
Harms H., Wells M.C., van der Meer J.R.
ISSN
0175-7598[print], 0175-7598[linking]
Statut éditorial
Publié
Date de publication
2006
Volume
70
Numéro
3
Pages
273-280
Langue
anglais
Résumé
Since the development of the first whole-cell living biosensor or bioreporter about 15 years ago, construction and testing of new genetically modified microorganisms for environmental sensing and reporting has proceeded at an ever increasing rate. One and a half decades appear as a reasonable time span for a new technology to reach the maturity needed for application and commercial success. It seems, however, that the research into cellular biosensors is still mostly in a proof-of-principle or demonstration phase and not close to extensive or commercial use outside of academia. In this review, we consider the motivations for bioreporter developments and discuss the suitability of extant bioreporters for the proposed applications to stimulate complementary research and to help researchers to develop realistic objectives. This includes the identification of some popular misconceptions about the qualities and shortcomings of bioreporters.
Mots-clé
Bacteria/cytology, Bacteria/genetics, Biosensing Techniques/methods, Environmental Monitoring/methods, Organisms, Genetically Modified
Pubmed
Web of science
Création de la notice
21/01/2008 14:36
Dernière modification de la notice
03/03/2018 21:05
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