Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Chemical sensing in Drosophila.
Current Opinion in Neurobiology
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Chemical sensing begins when peripheral receptor proteins recognise specific environmental stimuli and translate them into spatial and temporal patterns of sensory neuron activity. The chemosensory system of the fruit fly, Drosophila melanogaster, has become a dominant model to understand this process, through its accessibility to a powerful combination of molecular, genetic and electrophysiological analysis. Recent results have revealed many surprises in the biology of peripheral chemosensation in Drosophila, including novel structural and signalling properties of the insect odorant receptors (ORs), combinatorial mechanisms of chemical recognition by the gustatory receptors (GRs), and the implication of Transient Receptor Potential (TRP) ion channels as a novel class of chemosensory receptors.
Animals, Drosophila/genetics, Drosophila/physiology, Drosophila Proteins/genetics, Drosophila Proteins/physiology, Electrophysiology, Models, Biological, Receptors, Cell Surface/genetics, Receptors, Cell Surface/physiology, Receptors, Odorant/genetics, Receptors, Odorant/physiology, Sensory Receptor Cells/cytology, Sensory Receptor Cells/metabolism, Signal Transduction/genetics, Signal Transduction/physiology
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