Utility of a biopsy in suspicious pigmented iris tumors.

Détails

ID Serval
serval:BIB_BDF74A6DC3F8
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Utility of a biopsy in suspicious pigmented iris tumors.
Périodique
Ophthalmic Research
Auteur(s)
Schalenbourg A., Uffer S., Zografos L.
ISSN
1423-0259 (Electronic)
ISSN-L
0030-3747
Statut éditorial
Publié
Date de publication
2008
Volume
40
Numéro
5
Pages
267-272
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
WOS Document Type: Article
Résumé
BACKGROUND: In the presence of pigmented iris lesions evocative of malignant melanoma and implying oncological treatment, a foregoing biopsy to exclude a benign lesion may seem a reasonable approach. After examining patient files, the utility of such a diagnostic approach was explored.
MATERIAL AND METHODS: Retrospective, consecutive histopathologic case series of 10 pigmented iris tumor specimens excised since 1993. Histopathologic diagnosis was compared with final diagnosis and outcome in the patient's medical chart.
RESULTS: Five biopsies had only nevus cells, whereas ulterior clinical data or histopathologic examinations were compatible with the diagnosis of malignant melanoma. One biopsy contained insufficient sample tissue. Four biopsies confirmed clinical suspicion of iris melanoma.
CONCLUSION: In the current case series, 6 out of 10 biopsies provided a falsely reassuring negative or an inconclusive result. Modern management techniques such as ultrasound biomicroscopy and proton therapy of the whole anterior segment have equally diminished indications for a biopsy. In cases clinically evocative of iris melanoma, a biopsy has only a relative value.
Mots-clé
Adult, Biopsy, Eye Enucleation, Female, Humans, Iridectomy, Iris Neoplasms/pathology, Iris Neoplasms/radiotherapy, Male, Melanoma/pathology, Melanoma/radiotherapy, Microscopy, Acoustic, Middle Aged, Nevus, Pigmented/pathology, Nevus, Pigmented/radiotherapy, Protons, Retrospective Studies
Pubmed
Web of science
Création de la notice
22/01/2009 13:36
Dernière modification de la notice
03/03/2018 20:59
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