Etude de la variation interlaboratoire du test de dépistage prénatal des défauts de fermeture du tube neural [Interlaboratory variation in the prenatal screening test for neural tube closing defects].

Détails

ID Serval
serval:BIB_BD6D86462E25
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Etude de la variation interlaboratoire du test de dépistage prénatal des défauts de fermeture du tube neural [Interlaboratory variation in the prenatal screening test for neural tube closing defects].
Périodique
Sozial- Und Präventivmedizin
Auteur(s)
Braoudakis G., Marguerat P., Marazzi A., Gutzwiller F.
ISSN
0303-8408 (Print)
ISSN-L
0303-8408
Statut éditorial
Publié
Date de publication
1984
Volume
29
Numéro
4-5
Pages
207-208
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Publication types: English Abstract ; Journal Article In WOS under the title [Prenatal Alpha-Fetoprotein Screening For Open Neural-Tube Defects - Study of the Interlaboratory Variability]
Résumé
Early detection of neural-tude defects is possible by determining Alpha-fetoprotein (AFP) in maternal serum. 16'685 pregnant women were observed. Three methods for the determination of the "normal" range are compared. The first one, already used in similar studies, makes use of a constant multiple of the median. The other two ones make use of robust estimates of location and scale. Their comparison shows the interest of the robust methods to reduce the interlaboratory variability.
Mots-clé
Female, Humans, Laboratories/standards, Neural Tube Defects/diagnosis, Pregnancy, Prenatal Diagnosis/methods, Switzerland, alpha-Fetoproteins/analysis
Pubmed
Web of science
Création de la notice
08/09/2011 23:56
Dernière modification de la notice
03/03/2018 20:58
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