Function, evolution, and structure of J-domain proteins.

Détails

ID Serval
serval:BIB_BA8B22317801
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Function, evolution, and structure of J-domain proteins.
Périodique
Cell stress & chaperones
Auteur(s)
Kampinga H.H., Andreasson C., Barducci A., Cheetham M.E., Cyr D., Emanuelsson C., Genevaux P., Gestwicki J.E., Goloubinoff P., Huerta-Cepas J., Kirstein J., Liberek K., Mayer M.P., Nagata K., Nillegoda N.B., Pulido P., Ramos C., De Los Rios P., Rospert S., Rosenzweig R., Sahi C., Taipale M., Tomiczek B., Ushioda R., Young J.C., Zimmermann R., Zylicz A., Zylicz M., Craig E.A., Marszalek J.
ISSN
1466-1268 (Electronic)
ISSN-L
1355-8145
Statut éditorial
Publié
Date de publication
01/2019
Peer-reviewed
Oui
Volume
24
Numéro
1
Pages
7-15
Langue
anglais
Notes
Publication types: Congress ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
Hsp70 chaperone systems are very versatile machines present in nearly all living organisms and in nearly all intracellular compartments. They function in many fundamental processes through their facilitation of protein (re)folding, trafficking, remodeling, disaggregation, and degradation. Hsp70 machines are regulated by co-chaperones. J-domain containing proteins (JDPs) are the largest family of Hsp70 co-chaperones and play a determining role functionally specifying and directing Hsp70 functions. Many features of JDPs are not understood; however, a number of JDP experts gathered at a recent CSSI-sponsored workshop in Gdansk (Poland) to discuss various aspects of J-domain protein function, evolution, and structure. In this report, we present the main findings and the consensus reached to help direct future developments in the field of Hsp70 research.
Mots-clé
Animals, Disease, Evolution, Molecular, HSP70 Heat-Shock Proteins/chemistry, HSP70 Heat-Shock Proteins/classification, HSP70 Heat-Shock Proteins/metabolism, Humans, Protein Aggregates, Protein Domains, Protein Refolding, 8-stranded β-sandwich domain (SBDβ), Heat shock protein 70 (Hsp70), J-domain proteins (JDPs)
Pubmed
Web of science
Création de la notice
04/01/2019 15:13
Dernière modification de la notice
20/08/2019 16:28
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