Traitement hormonal de la ménopause : effets osseux et sur la composition corporelle [Menopausal hormone therapy. Effects on bone and body composition]

Détails

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Etat: Public
Version: de l'auteur
Licence: Non spécifiée
ID Serval
serval:BIB_BA78B0DCA756
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Traitement hormonal de la ménopause : effets osseux et sur la composition corporelle [Menopausal hormone therapy. Effects on bone and body composition]
Périodique
Revue medicale suisse
Auteur(s)
Papadakis G., Gonzalez Rodriguez E., Marques-Vidal P., Hans D., Vollenweider P., Waeber G., Lamy O.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
17/04/2019
Peer-reviewed
Oui
Volume
15
Numéro
647
Pages
836-839
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Changes occurring at menopause can be mitigated by prescribing menopausal hormone replacement therapy (HRT). Recent publications from the CoLaus/OsteoLaus cohorts provide important insights into the effects of HRT and after its discontinuation on bone and body composition. HRT has a beneficial effect on bone mineral density, bone microarchitecture and fracture prevention. The benefits persist after treatment discontinuation, but not beyond 2 to 5 years. The effect of HRT on body composition is more controversial. HRT reduces the accumulation of fat mass, mainly abdominal and visceral fat mass. This is important from the perspective of diabetes and cardiovascular disease prevention. However, the benefits seem to disappear immediately after discontinuation.
Mots-clé
Body Composition/drug effects, Bone Density, Bone and Bones, Estrogen Replacement Therapy, Female, Hormone Replacement Therapy, Humans, Menopause
Pubmed
Création de la notice
28/04/2019 14:12
Dernière modification de la notice
23/01/2020 6:19
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