Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes.

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Ressource 1Download: BIB_BA3AB46589C1.P001.pdf (1098.91 [Ko])
State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_BA3AB46589C1
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Ureaplasma urealyticum, Mycoplasma hominis and adverse pregnancy outcomes.
Journal
Current Opinion in Infectious Diseases
Author(s)
Capoccia R., Greub G., Baud D.
ISSN
1473-6527 (Electronic)
ISSN-L
0951-7375
Publication state
Published
Issued date
2013
Volume
26
Number
3
Pages
231-240
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish. PDF type: Review
Abstract
PURPOSE OF REVIEW: Mycoplasma hominis and Ureaplasma urealyticum may colonize the human genital tract and have been associated with adverse pregnancy outcomes. Chorioamnionitis, spontaneous preterm labour and preterm premature rupture of membranes are significant contributors to neonatal morbidity and mortality. However, as these bacteria can reside in the normal vaginal flora, there are controversies regarding their true role during pregnancy and thus the need to treat these organisms.
RECENT FINDINGS: We review here the recent data on the epidemiology of mycoplasmas and their clinical role during pregnancy. The association of these organisms with preterm labour has been suggested by many observational studies, but proof of causality remains limited. PCR is an excellent alternative to culture to detect the presence of these organisms, but culture allows antibiotic susceptibility testing. Whether antimicrobial treatment of mycoplasma-colonized pregnant patients can effectively reduce the incidence of adverse pregnancy outcomes warrants further investigations.
SUMMARY: The role of Mycoplasma spp. and U. urealyticum in adverse pregnancy outcomes is increasingly accepted. However, sole presence of these microorganisms in the vaginal flora might be insufficient to cause pathological issues, but their combination with other factors such as bacterial vaginosis or cervical incompetence may be additionally needed to induce preterm birth.
Pubmed
Web of science
Open Access
Yes
Create date
31/05/2013 16:05
Last modification date
20/08/2019 15:28
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