Pain relief and respiratory mechanics during continuous intrapleural bupivacaine administration after thoracotomy

Détails

ID Serval
serval:BIB_BA0D5E93A80F
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Pain relief and respiratory mechanics during continuous intrapleural bupivacaine administration after thoracotomy
Périodique
Thoracic and Cardiovascular Surgeon
Auteur(s)
Inderbitzi  R., Flueckiger  K., Ris  H. B.
ISSN
0171-6425 (Print)
Statut éditorial
Publié
Date de publication
04/1992
Volume
40
Numéro
2
Pages
87-9
Notes
Clinical Trial
Journal Article
Randomized Controlled Trial --- Old url value: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1631878 --- Old month value: Apr
Résumé
Continuous intrapleural bupivacaine administration was assessed in a randomized double-blind manner with respect to its analgesic effect and its impact on breathing after thoracotomy. The pleural cavity was infused continuously for 48 hours in 24 patients following thoracotomy for pulmonary resection. 12 patients received 10 ml/h of bupivacaine hydrochloride 0.5% solution, and 12 patients 10 ml/h NaCl 0.9% solution. There were no differences in the patients' characteristics, extent of surgery, mode and duration of general anaesthesia. There were no complications related either to the catheter or to bupivacaine. The amount of postoperative opioid, given on request, was used to assess the effect of bupivacaine administration on pain relief. Post-thoracotomy breathing was assessed by measuring the forced vital capacity (VC) prior to and after physiotherapy. The VC values measured 24 h, 36 h and 48 h after the operation were similar in both groups of patients with or without bupivacaine administration (p greater than 0.05). Patients given bupivacaine required significantly less opioid analgesia than those who received NaCl 0.9% at 24 h (p less than 0.001), 36 h (p less than 0.001) and 48 h (p less than 0.01) after the operation. Continuous intrapleural bupivacaine analgesia through a paravertebral catheter positioned in the paravertebral groove is safe and provides efficient pain relief after thoracotomy.
Mots-clé
Aged Bupivacaine/*administration & dosage Female Humans Infusion Pumps, Implantable Infusions, Parenteral/*methods Male Middle Aged Pain/*drug therapy/etiology *Pleura Postoperative Care/methods Respiratory Mechanics/*drug effects Thoracotomy/*adverse effects
Pubmed
Web of science
Création de la notice
29/01/2008 13:59
Dernière modification de la notice
03/03/2018 20:52
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