Differentiation of heroin and cocaine using dual-energy CT-an experimental study.

Détails

ID Serval
serval:BIB_BA0866FF59A6
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Differentiation of heroin and cocaine using dual-energy CT-an experimental study.
Périodique
International Journal of Legal Medicine
Auteur(s)
Grimm J., Wudy R., Ziegeler E., Wirth S., Uhl M., Reiser M.F., Scherr M.
ISSN
1437-1596 (Electronic)
ISSN-L
0937-9827
Statut éditorial
Publié
Date de publication
2014
Volume
128
Numéro
3
Pages
475-482
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish PDF: Original Article
Résumé
OBJECTIVE: To evaluate if heroin and cocaine can be distinguished using dual-energy CT.
MATERIALS AND METHODS: Twenty samples of heroin and cocaine at different concentrations and standardized compression (SC) were scanned in dual-energy mode on a newest generation Dual Energy 64-row MDCT scanner. CT number, spectral graphs, and dual-energy index (DEI) were evaluated. Results were prospectively tested on six original samples from a body packer. Wilcoxon's test was used for statistical evaluation.
RESULTS: Values are given as median and range. Under SC, the CT number of cocaine samples (-29.87 Hounsfield unit (HU) [-125.85; 16.16 HU]) was higher than the CT number of heroin samples (-184.37 HU [-199.81; -159.25 HU]; p < 0.01). Slope of spectral curves for cocaine was -2.36 HU/keV [-7.15; -0.67 HU/keV], and for heroin, 1.75 HU/keV [1.28; 2.5 HU/keV] (p < 0.01). DEI was 0.0352 [0.0081; 0.0528] for cocaine and significantly higher than for heroin samples (-0.0127 [-0.0097; -0.0159]; p < 0.001). While CT number was inconclusive, all six original packs were correctly classified after evaluation of the spectral curve and DEI. In contrast to the CT number, slope of the spectral curve and DEI were independent of concentration and compression.
CONCLUSION: The slope of the spectral curve and the DEI from dual-energy CT data can be used to distinguish heroin and cocaine in vitro; these results are independent of compression and concentration in the measured range.
Mots-clé
forensic medicine
Pubmed
Web of science
Création de la notice
06/06/2014 17:35
Dernière modification de la notice
20/08/2019 16:28
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