Trajectory and predictors of quality of life in first episode psychotic mania.

Détails

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Etat: Public
Version: Author's accepted manuscript
ID Serval
serval:BIB_B9D04D634EEC
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Trajectory and predictors of quality of life in first episode psychotic mania.
Périodique
Journal of Affective Disorders
Auteur(s)
Oldis M., Murray G., Macneil C.A., Hasty M.K., Daglas R., Berk M., Conus P., Cotton S.M.
ISSN
1573-2517 (Electronic)
ISSN-L
0165-0327
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
195
Pages
148-155
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
BACKGROUND: Little is known about the trajectory of quality of life (QoL) following a first episode of psychotic mania in bipolar disorder (BD). This 18-month longitudinal study investigated the trajectory of QoL, and the influence of premorbid adjustment and symptoms on 18-month QoL in a cohort of young people experiencing a first episode of psychotic mania.
METHODS: As part of an overarching clinical trial, at baseline, sixty participants presenting with a first episode of psychotic mania (BD Type 1 - DSM-IV) completed symptomatic and functional assessments in addition to the Premorbid Adjustment Scale - General Subscale. Symptom measures were repeated at 18-month follow up. QoL was rated using the Quality of Life Scale (QLS) at designated time points.
RESULTS: Mean QLS scores at initial measurement (8 weeks) were 61% of the maximum possible score, increasing significantly to 70% at 12 months, and 71.2% at 18-month follow-up. Premorbid adjustment and 18-month depressive symptoms were significantly associated with QoL at 18-month follow-up.
LIMITATIONS: Study limitations include the small sample size, inclusion of participants with psychotic mania only, use of measures originally designed for use with schizophrenia spectrum disorders, and lack of premorbid or baseline measurement of QoL.
CONCLUSIONS: Results suggest that QoL can be maintained early in BD, and reinforce the importance of assertively treating depressive symptoms throughout the course of this disorder. The emergence of a link between premorbid adjustment and poorer QoL in this cohort highlights the importance of assessing facets of adjustment when planning psychological interventions.
Mots-clé
Adolescent, Adult, Bipolar Disorder/complications, Bipolar Disorder/psychology, Cohort Studies, Depression/complications, Depression/psychology, Diagnostic and Statistical Manual of Mental Disorders, Disease Progression, Employment, Female, Humans, Longitudinal Studies, Male, Predictive Value of Tests, Psychotic Disorders/complications, Psychotic Disorders/psychology, Quality of Life/psychology, Schizophrenic Psychology, Social Behavior, Socioeconomic Factors, Young Adult
Pubmed
Web of science
Open Access
Oui
Création de la notice
22/02/2016 17:52
Dernière modification de la notice
20/08/2019 16:27
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