Paraneoplastic syndromes in ganglioneuroblastoma: contrasting symptoms of constipation and diarrhoea.

Details

Serval ID
serval:BIB_B97911A5A4E9
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Paraneoplastic syndromes in ganglioneuroblastoma: contrasting symptoms of constipation and diarrhoea.
Journal
European Journal of Pediatrics
Author(s)
Wildhaber B., Niggli F., Bergsträsser E., Stallmach T., Sacher P.
ISSN
0340-6199 (Print)
ISSN-L
0340-6199
Publication state
Published
Issued date
2003
Peer-reviewed
Oui
Volume
162
Number
7-8
Pages
511-513
Language
english
Notes
Publication types: Case Reports ; Journal Article Publication Status: ppublish
Abstract
A paraneoplastic syndrome is occasionally the first clinical symptom seen with tumours. We report on two children who initially presented with paraneoplastic syndromes due to ganglioneuroblastomas: the first with severe watery diarrhoea caused by a ganglioneuroma producing vasoactive intestinal peptide, the second with non-treatable constipation, caused by ganglioneuroma-produced anti-neuronal nuclear antibodies.
CONCLUSION: Either severe diarrhoea or chronic constipation may represent rare paraneoplastic syndromes in ganglioneuroblastomas.
Keywords
Adolescent, Adrenal Gland Neoplasms/complications, Adrenal Gland Neoplasms/metabolism, Chronic Disease, Constipation/etiology, Fatal Outcome, Female, Ganglioneuroblastoma/complications, Ganglioneuroblastoma/metabolism, Humans, Infant, Paraneoplastic Syndromes/diagnosis, Vasoactive Intestinal Peptide/metabolism, Vomiting/etiology
Pubmed
Web of science
Create date
21/02/2015 12:23
Last modification date
20/08/2019 15:27
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