Esophageal cancer T-staging on MRI: A preliminary study using cine and static MR sequences.

Details

Ressource 1Download: 37516096.pdf (4242.97 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_B3DB02D052A3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Esophageal cancer T-staging on MRI: A preliminary study using cine and static MR sequences.
Journal
European journal of radiology
Author(s)
Haefliger L., Jreige M., Du Pasquier C., Ledoux J.B., Wagner D., Mantziari S., Shäfer M., Vietti Violi N., Dromain C.
ISSN
1872-7727 (Electronic)
ISSN-L
0720-048X
Publication state
Published
Issued date
09/2023
Peer-reviewed
Oui
Volume
166
Pages
111001
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
To evaluate the added value of cine MR in addition to static MRI for T-Staging assessment of esophageal cancer (EC).
This prospective monocentric study included 54 patients (mean age 66.3 ± 9.4 years, 46 men) with histologically proven EC. They underwent MRI on a 3 T-scanner in addition to the standard workup. Acquisitions included static and cine sequences (steady-state-free-precession and real-time True-FISP during water ingestion). Three radiologists independently assessed T-staging and diagnosis confidence by reviewing (1) static sequences (S-MRI) and (2) adding cine sequences (SC-MRI). Inter-reader agreement was performed. MRI T-staging was correlated to reference standard T-staging (histopathology or consensus on endoscopic ultrasonography and imaging findings) and to clinical outcome by log-rank test.
Both S-MRI and SC-MRI T-staging showed a significant correlation with reference T-staging (rs = 0.667, P < 0.001). SC-MRI showed a slightly better performance in distinguishing T1-T3 from T4 with a sensitivity, specificity and AUC of 76.5% (95% CI: 50.1-93.2), 83.8% (68-93.8) and 0.801 (0.681-0.921) vs 70.6% (44-89.7), 83% (68-93.8) and 0.772 (0.645-0.899) for S-MRI. Compared to S-MRI, SC-MRI increased inter-reader agreement for T4a and T4b (κ = 0.403 and 0.498) and T-staging confidence.
MRI is accurate for T-staging of EC. The addition of cine sequences allows better differentiation between T1-T3 and T4 tumors with increased diagnostic confidence and inter-reader agreement.
Keywords
Male, Humans, Middle Aged, Aged, Prospective Studies, Neoplasm Staging, Magnetic Resonance Imaging/methods, Esophageal Neoplasms/diagnostic imaging, Esophageal Neoplasms/pathology, Endosonography/methods, Sensitivity and Specificity, Cine MRI, Esophageal neoplasm, Tumor staging
Pubmed
Web of science
Open Access
Yes
Create date
21/07/2023 16:06
Last modification date
29/02/2024 16:57
Usage data