CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Details
State: Public
Version: Final published version
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_B3A5C856592D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.
Journal
Cardiovascular Research
ISSN
1755-3245[electronic], 0008-6363[linking]
Publication state
Published
Issued date
2010
Volume
85
Number
4
Pages
773-784
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't Publication
Keywords
Amidohydrolases/metabolism, Animals, Antibiotics, Antineoplastic/toxicity, Apoptosis/physiology, Cardiomyopathies/chemically induced, Cardiomyopathies/metabolism, Caspase 3/metabolism, Caspase 7/metabolism, Cells, Cultured, Cytochromes c/metabolism, Disease Models, Animal, Doxorubicin/toxicity, Endocannabinoids/metabolism, Endomyocardial Fibrosis/chemically induced, Endomyocardial Fibrosis/metabolism, Humans, MAP Kinase Signaling System/physiology, Male, Mice, Mice, Knockout, Myocytes, Cardiac/cytology, Myocytes, Cardiac/metabolism, Oxidative Stress/physiology, Poly(ADP-ribose) Polymerases/metabolism, Reactive Nitrogen Species/metabolism, Reactive Oxygen Species/metabolism, Receptor, Cannabinoid, CB1/genetics, Receptor, Cannabinoid, CB1/metabolism, Ventricular Function, Left/physiology
Pubmed
Web of science
Open Access
Yes
Create date
09/03/2011 9:20
Last modification date
14/02/2022 7:56
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