Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality.

Nguyen, T.N.; Qureshi, M.M.; Klein, P.; Yamagami, H.; Abdalkader, M.; Mikulik, R.; Sathya, A.; Mansour, O.Y.; Czlonkowska, A.; Lo, H.; Field, T.S.; Charidimou, A.; Banerjee, S.; Yaghi, S.; Siegler, J.E.; Sedova, P.; Kwan, J.; de Sousa, D.A.; Demeestere, J.; Inoa, V.; Omran, S.S.; Zhang, L.; Michel, P.; Strambo, D.; Marto, J.P.; Nogueira, R.G.; Kristoffersen, E.S.; Tsivgoulis, G.; Lereis, V.P.; Ma, A.; Enzinger, C.; Gattringer, T.; Rahman, A.; Bonnet, T.; Ligot, N.; De Raedt, S.; Lemmens, R.; Vanacker, P.; Vandervorst, F.; Conforto, A.B.; Hidalgo, RCT; Mora Cuervo, D.L.; de Oliveira Neves, L.; Lameirinhas da Silva, I.; Martíns, R.T.; Rebello, L.C.; Santiago, I.B.; Sakelarova, T.; Kalpachki, R.; Alexiev, F.; Cora, E.A.; Kelly, M.E.; Peeling, L.; Pikula, A.; Chen, H.S.; Chen, Y.; Yang, S.; Roje Bedekovic, M.; Čabal, M.; Tenora, D.; Fibrich, P.; Dušek, P.; Hlaváčová, H.; Hrabanovska, E.; Jurák, L.; Kadlčíková, J.; Karpowicz, I.; Klečka, L.; Kovář, M.; Neumann, J.; Paloušková, H.; Reiser, M.; Rohan, V.; Šimůnek, L.; Skoda, O.; Škorňa, M.; Šrámek, M.; Drenck, N.; Sobh, K.; Lesaine, E.; Sabben, C.; Reiner, P.; Rouanet, F.; Strbian, D.; Boskamp, S.; Mbroh, J.; Nagel, S.; Rosenkranz, M.; Poli, S.; Thomalla, G.; Karapanayiotides, T.; Koutroulou, I.; Kargiotis, O.; Palaiodimou, L.; Barrientos Guerra, J.D.; Huded, V.; Nagendra, S.; Prajapati, C.; Sylaja, P.N.; Sani, A.F.; Ghoreishi, A.; Farhoudi, M.; Sadeghi Hokmabadi, E.; Hashemilar, M.; Sabetay, S.I.; Rahal, F.; Acampa, M.; Adami, A.; Longoni, M.; Ornello, R.; Renieri, L.; Romoli, M.; Sacco, S.; Salmaggi, A.; Sangalli, D.; Zini, A.; Sakai, K.; Fukuda, H.; Fujita, K.; Imamura, H.; Kosuke, M.; Sakaguchi, M.; Sonoda, K.; Matsumaru, Y.; Ohara, N.; Shindo, S.; Takenobu, Y.; Yoshimoto, T.; Toyoda, K.; Uwatoko, T.; Sakai, N.; Yamamoto, N.; Yamamoto, R.; Yazawa, Y.; Sugiura, Y.; Baek, J.H.; Lee, S.B.; Seo, K.D.; Sohn, S.I.; Lee, J.S.; Arsovska, A.A.; Chieh, C.Y.; Wan Zaidi, W.A.; Wan Yahya, WNN; Gongora-Rivera, F.; Martinez-Marino, M.; Infante-Valenzuela, A.; Dippel, D.; van Dam-Nolen, DHK; Wu, T.Y.; Punter, M.; Adebayo, T.T.; Bello, A.H.; Sunmonu, T.A.; Wahab, K.W.; Sundseth, A.; Al Hashmi, A.M.; Ahmad, S.; Rashid, U.; Rodriguez-Kadota, L.; Vences, M.Á.; Yalung, P.M.; Dy, JSH; Brola, W.; Dębiec, A.; Dorobek, M.; Karlinski, M.A.; Labuz-Roszak, B.M.; Lasek-Bal, A.; Sienkiewicz-Jarosz, H.; Staszewski, J.; Sobolewski, P.; Wiącek, M.; Zielinska-Turek, J.; Araújo, A.P.; Rocha, M.; Castro, P.; Ferreira, P.; Nunes, A.P.; Fonseca, L.; Pinho E Melo, T.; Rodrigues, M.; Silva, M.L.; Ciopleias, B.; Dimitriade, A.; Falup-Pecurariu, C.; Hamid, M.A.; Venketasubramanian, N.; Krastev, G.; Haring, J.; Ayo-Martin, O.; Hernandez-Fernandez, F.; Blasco, J.; Rodríguez-Vázquez, A.; Cruz-Culebras, A.; Moniche, F.; Montaner, J.; Perez-Sanchez, S.; García Sánchez, M.J.; Guillán Rodríguez, M.; Bernava, G.; Bolognese, M.; Carrera, E.; Churojana, A.; Aykac, O.; Özdemir, A.Ö.; Bajrami, A.; Senadim, S.; Hussain, S.I.; John, S.; Krishnan, K.; Lenthall, R.; Asif, K.S.; Below, K.; Biller, J.; Chen, M.; Chebl, A.; Colasurdo, M.; Czap, A.; de Havenon, A.H.; Dharmadhikari, S.; Eskey, C.J.; Farooqui, M.; Feske, S.K.; Goyal, N.; Grimmett, K.B.; Guzik, A.K.; Haussen, D.C.; Hovingh, M.; Jillela, D.; Kan, P.T.; Khatri, R.; Khoury, N.N.; Kiley, N.L.; Kolikonda, M.K.; Lara, S.; Li, G.; Linfante, I.; Loochtan, A.I.; Lopez, C.D.; Lycan, S.; Male, S.S.; Nahab, F.; Maali, L.; Masoud, H.E.; Min, J.; Orgeta-Gutierrez, S.; Mohamed, G.A.; Mohammaden, M.; Nalleballe, K.; Radaideh, Y.; Ramakrishnan, P.; Rayo-Taranto, B.; Rojas-Soto, D.M.; Ruland, S.; Simpkins, A.N.; Sheth, S.A.; Starosciak, A.K.; Tarlov, N.E.; Taylor, R.A.; Voetsch, B.; Zhang, L.; Duong, H.Q.; Dao, V.P.; Le, H.V.; Pham, T.N.; Ton, M.D.; Tran, A.D.; Zaidat, O.O.; Machi, P.; Dirren, E.; Rodríguez Fernández, C.; Escartín López, J.; Fernández Ferro, J.C.; Mohammadzadeh, N.; Suryadevara, N.C.; de la Cruz Fernández, B.; Bessa, F.; Jancar, N.; Brady, M.; Scozzari, D.

doi:10.5853/jos.2022.00752

Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality.

Details

Download: 35677980_BIB_B20CFC53D2A7.pdf (237.13 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0

Serval ID

serval:BIB_B20CFC53D2A7

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Global Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality.

Journal

Journal of stroke

Author(s)

Nguyen T.N., Qureshi M.M., Klein P., Yamagami H., Abdalkader M., Mikulik R., Sathya A., Mansour O.Y., Czlonkowska A., Lo H., Field T.S., Charidimou A., Banerjee S., Yaghi S., Siegler J.E., Sedova P., Kwan J., de Sousa D.A., Demeestere J., Inoa V., Omran S.S., Zhang L., Michel P., Strambo D., Marto J.P., Nogueira R.G., Kristoffersen E.S., Tsivgoulis G., Lereis V.P., Ma A., Enzinger C., Gattringer T., Rahman A., Bonnet T., Ligot N., De Raedt S., Lemmens R., Vanacker P., Vandervorst F., Conforto A.B., Hidalgo RCT, Mora Cuervo D.L., de Oliveira Neves L., Lameirinhas da Silva I., Martíns R.T., Rebello L.C., Santiago I.B., Sakelarova T., Kalpachki R., Alexiev F., Cora E.A., Kelly M.E., Peeling L., Pikula A., Chen H.S., Chen Y., Yang S., Roje Bedekovic M., Čabal M., Tenora D., Fibrich P., Dušek P., Hlaváčová H., Hrabanovska E., Jurák L., Kadlčíková J., Karpowicz I., Klečka L., Kovář M., Neumann J., Paloušková H., Reiser M., Rohan V., Šimůnek L., Skoda O., Škorňa M., Šrámek M., Drenck N., Sobh K., Lesaine E., Sabben C., Reiner P., Rouanet F., Strbian D., Boskamp S., Mbroh J., Nagel S., Rosenkranz M., Poli S., Thomalla G., Karapanayiotides T., Koutroulou I., Kargiotis O., Palaiodimou L., Barrientos Guerra J.D., Huded V., Nagendra S., Prajapati C., Sylaja P.N., Sani A.F., Ghoreishi A., Farhoudi M., Sadeghi Hokmabadi E., Hashemilar M., Sabetay S.I., Rahal F., Acampa M., Adami A., Longoni M., Ornello R., Renieri L., Romoli M., Sacco S., Salmaggi A., Sangalli D., Zini A., Sakai K., Fukuda H., Fujita K., Imamura H., Kosuke M., Sakaguchi M., Sonoda K., Matsumaru Y., Ohara N., Shindo S., Takenobu Y., Yoshimoto T., Toyoda K., Uwatoko T., Sakai N., Yamamoto N., Yamamoto R., Yazawa Y., Sugiura Y., Baek J.H., Lee S.B., Seo K.D., Sohn S.I., Lee J.S., Arsovska A.A., Chieh C.Y., Wan Zaidi W.A., Wan Yahya WNN, Gongora-Rivera F., Martinez-Marino M., Infante-Valenzuela A., Dippel D., van Dam-Nolen DHK, Wu T.Y., Punter M., Adebayo T.T., Bello A.H., Sunmonu T.A., Wahab K.W., Sundseth A., Al Hashmi A.M., Ahmad S., Rashid U., Rodriguez-Kadota L., Vences M.Á., Yalung P.M., Dy JSH, Brola W., Dębiec A., Dorobek M., Karlinski M.A., Labuz-Roszak B.M., Lasek-Bal A., Sienkiewicz-Jarosz H., Staszewski J., Sobolewski P., Wiącek M., Zielinska-Turek J., Araújo A.P., Rocha M., Castro P., Ferreira P., Nunes A.P., Fonseca L., Pinho E Melo T., Rodrigues M., Silva M.L., Ciopleias B., Dimitriade A., Falup-Pecurariu C., Hamid M.A., Venketasubramanian N., Krastev G., Haring J., Ayo-Martin O., Hernandez-Fernandez F., Blasco J., Rodríguez-Vázquez A., Cruz-Culebras A., Moniche F., Montaner J., Perez-Sanchez S., García Sánchez M.J., Guillán Rodríguez M., Bernava G., Bolognese M., Carrera E., Churojana A., Aykac O., Özdemir A.Ö., Bajrami A., Senadim S., Hussain S.I., John S., Krishnan K., Lenthall R., Asif K.S., Below K., Biller J., Chen M., Chebl A., Colasurdo M., Czap A., de Havenon A.H., Dharmadhikari S., Eskey C.J., Farooqui M., Feske S.K., Goyal N., Grimmett K.B., Guzik A.K., Haussen D.C., Hovingh M., Jillela D., Kan P.T., Khatri R., Khoury N.N., Kiley N.L., Kolikonda M.K., Lara S., Li G., Linfante I., Loochtan A.I., Lopez C.D., Lycan S., Male S.S., Nahab F., Maali L., Masoud H.E., Min J., Orgeta-Gutierrez S., Mohamed G.A., Mohammaden M., Nalleballe K., Radaideh Y., Ramakrishnan P., Rayo-Taranto B., Rojas-Soto D.M., Ruland S., Simpkins A.N., Sheth S.A., Starosciak A.K., Tarlov N.E., Taylor R.A., Voetsch B., Zhang L., Duong H.Q., Dao V.P., Le H.V., Pham T.N., Ton M.D., Tran A.D., Zaidat O.O., Machi P., Dirren E., Rodríguez Fernández C., Escartín López J., Fernández Ferro J.C., Mohammadzadeh N., Suryadevara N.C., de la Cruz Fernández B., Bessa F., Jancar N., Brady M., Scozzari D.

Working group(s)

SVIN COVID-19 Global COVID Stroke Registry

ISSN

2287-6391 (Print)

ISSN-L

2287-6391

Publication state

Published

Issued date

05/2022

Peer-reviewed

Oui

Volume

Number

Pages

256-265

Language

english

Notes

Publication types: Journal Article
Publication Status: ppublish

Abstract

Recent studies suggested an increased incidence of cerebral venous thrombosis (CVT) during the coronavirus disease 2019 (COVID-19) pandemic. We evaluated the volume of CVT hospitalization and in-hospital mortality during the 1st year of the COVID-19 pandemic compared to the preceding year.
We conducted a cross-sectional retrospective study of 171 stroke centers from 49 countries. We recorded COVID-19 admission volumes, CVT hospitalization, and CVT in-hospital mortality from January 1, 2019, to May 31, 2021. CVT diagnoses were identified by International Classification of Disease-10 (ICD-10) codes or stroke databases. We additionally sought to compare the same metrics in the first 5 months of 2021 compared to the corresponding months in 2019 and 2020 (ClinicalTrials.gov Identifier: NCT04934020).
There were 2,313 CVT admissions across the 1-year pre-pandemic (2019) and pandemic year (2020); no differences in CVT volume or CVT mortality were observed. During the first 5 months of 2021, there was an increase in CVT volumes compared to 2019 (27.5%; 95% confidence interval [CI], 24.2 to 32.0; P<0.0001) and 2020 (41.4%; 95% CI, 37.0 to 46.0; P<0.0001). A COVID-19 diagnosis was present in 7.6% (132/1,738) of CVT hospitalizations. CVT was present in 0.04% (103/292,080) of COVID-19 hospitalizations. During the first pandemic year, CVT mortality was higher in patients who were COVID positive compared to COVID negative patients (8/53 [15.0%] vs. 41/910 [4.5%], P=0.004). There was an increase in CVT mortality during the first 5 months of pandemic years 2020 and 2021 compared to the first 5 months of the pre-pandemic year 2019 (2019 vs. 2020: 2.26% vs. 4.74%, P=0.05; 2019 vs. 2021: 2.26% vs. 4.99%, P=0.03). In the first 5 months of 2021, there were 26 cases of vaccine-induced immune thrombotic thrombocytopenia (VITT), resulting in six deaths.
During the 1st year of the COVID-19 pandemic, CVT hospitalization volume and CVT in-hospital mortality did not change compared to the prior year. COVID-19 diagnosis was associated with higher CVT in-hospital mortality. During the first 5 months of 2021, there was an increase in CVT hospitalization volume and increase in CVT-related mortality, partially attributable to VITT.

Keywords

COVID-19, Cerebral venous thrombosis, Mortality, SARS-CoV-2, Stroke, Vaccine-induced immune thrombotic thrombocytopenia

URN

urn:nbn:ch:serval-BIB_B20CFC53D2A74

OAI-PMH

oai:serval.unil.ch:BIB_B20CFC53D2A7

DOI

10.5853/jos.2022.00752

Pubmed

35677980

Web of science

000812327500008