Multipoint linkage mapping of the Xq25-q26 region in a family affected by the X-linked lymphoproliferative syndrome
Details
Serval ID
serval:BIB_B1CFC3D7D026
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Multipoint linkage mapping of the Xq25-q26 region in a family affected by the X-linked lymphoproliferative syndrome
Journal
Clinical Genetics
ISSN
0009-9163 (Print)
Publication state
Published
Issued date
12/1989
Volume
36
Number
6
Pages
459-62
Notes
Journal Article --- Old month value: Dec
Abstract
We have performed, in a large Swiss family, a study of linkage between various DNA markers in the Xq24-27 region and the locus for the X-linked lymphoproliferative syndrome (XLP). Our results indicated that the marker DXS37 in Xq25-q26 is genetically linked to the XLP syndrome. The multipoint linkage analysis showed that the disease locus is distal to DXS11, but proximal to the hypoxanthine phosphoribosyl-transferase gene (HPRT).
Keywords
Female
Genetic Markers
Herpesvirus 4, Human/genetics
Humans
*Linkage (Genetics)
*Lod Score
Lymphoproliferative Disorders/*genetics
Male
Pedigree
Polymorphism, Restriction Fragment Length
Restriction Mapping
*X Chromosome
Pubmed
Web of science
Create date
17/01/2008 17:38
Last modification date
20/08/2019 16:20
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