The Impact of Diet on Immunity and Respiratory Diseases.
Details
Serval ID
serval:BIB_B144820AF1C9
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The Impact of Diet on Immunity and Respiratory Diseases.
Journal
Annals of the American Thoracic Society
ISSN
2325-6621 (Electronic)
ISSN-L
2325-6621
Publication state
Published
Issued date
11/2017
Peer-reviewed
Oui
Volume
14
Number
Supplement_5
Pages
S339-S347
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
The Western world has witnessed a tremendous increase in the occurrence of allergy and autoimmunity in the second half of the 20th century. Extensive efforts have been made to explain this phenomenon and various hypotheses have been formulated. Among them, two concepts have attracted the most attention: the "hygiene hypothesis," identifying the reduced exposure to environmental microorganisms as a driving force behind the observed epidemiological trends; and the "diet hypotheses," pointing to the importance of changes in our dietary habits. In this review, we discuss the interplay between the Western diet, microbiota, and inflammatory conditions, with particular emphasis on respiratory diseases. This is followed by an in-depth overview of the immunomodulatory potential of different dietary fatty acids. We conclude by identifying the outstanding questions, which, if answered, could shed further light on the impact of dietary habits on immunity and interconnect it with postulates proposed by the hygiene hypothesis. Linking these two concepts will be an important step towards understanding how Western lifestyle shapes disease susceptibility.
Keywords
Autoimmunity, Diet, Western, Dietary Fats, Disease Susceptibility, Fatty Acids/immunology, Gastrointestinal Microbiome/immunology, Humans, Hygiene Hypothesis, Life Style, Lung Diseases/etiology, Lung Diseases/immunology, Western diet, fatty acids, microbiome
Pubmed
Web of science
Create date
23/11/2017 18:34
Last modification date
29/04/2022 15:58