Determination of <sup>226</sup>Ra at low levels in environmental, urine, and human bone samples and <sup>223</sup>Ra in bone biopsy using alpha-spectrometry and metrological traceability to <sup>229</sup>Th/<sup>225</sup>Ra or <sup>226</sup>Ra.

Détails

ID Serval
serval:BIB_B126941C5045
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Determination of <sup>226</sup>Ra at low levels in environmental, urine, and human bone samples and <sup>223</sup>Ra in bone biopsy using alpha-spectrometry and metrological traceability to <sup>229</sup>Th/<sup>225</sup>Ra or <sup>226</sup>Ra.
Périodique
Analytica chimica acta
Auteur(s)
Straub M., Pittet P.A., Amzalag G., Bochud F., Baechler S., Froidevaux P.
ISSN
1873-4324 (Electronic)
ISSN-L
0003-2670
Statut éditorial
Publié
Date de publication
15/11/2018
Peer-reviewed
Oui
Volume
1031
Pages
178-184
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
<sup>226</sup> Ra is a natural radioelement emitting α and γ radiations. It can be highly concentrated in TENORM materials from the petroleum or fertilizer industries. In Switzerland, <sup>226</sup> Ra is currently a radioactive inheritance problem from the watch industry. Furthermore, <sup>223</sup> Ra is a radium isotope used in nuclear medicine to treat bone metastasis. There exist several methods to measure radium using alpha or gamma spectrometry or using <sup>222</sup> Rn emanation technique. The limitations of these methods are due to the required detection limits and the nature of the samples. When using alpha spectrometry to reach very low detection limits, critical technical hitches often arise because of the difficulties in separating radium from barium, in removing organics eluted from the separating chromatography column, and in plating radium. Moreover, overall chemical recovery of radium is often not reproducible, depending on the studies. Here we propose a method that separates radium from other alkaline-earth cations using cation exchange chromatography and selective complex formation by EDTA and DCTA. Radium is completely free of the <sup>229</sup> Th tracer and its daughter products, particularly <sup>225</sup> Ac. Organics from the column are removed in a further purification step so that radium can be plated with acceptable yields in a HCl/HNO <sub>3</sub> /ethanol solution. We successfully applied the method to soil, water, urine and human bone samples and further extended it to the determination of <sup>223</sup> Ra in a bone biopsy, using <sup>226</sup> Ra as an internal tracer.
Mots-clé
Alpha Particles, Bone and Bones/chemistry, Bone and Bones/metabolism, Bone and Bones/pathology, Gamma Rays, Humans, Radium/analysis, Radium/blood, Radium/urine, Scintillation Counting, Soil/chemistry, Thorium/analysis, Thorium/blood, Thorium/urine, Water Pollutants, Radioactive/analysis, Alpha spectrometry, Bone, Electrodeposition, Ra-223, Ra-226, Urine
Pubmed
Web of science
Création de la notice
31/08/2018 12:10
Dernière modification de la notice
30/10/2018 7:26
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