To what extent does adding tobacco to cannabis expose young users to nicotine?

Détails

ID Serval
serval:BIB_B06FC13752D1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
To what extent does adding tobacco to cannabis expose young users to nicotine?
Périodique
Nicotine and Tobacco Research
Auteur(s)
Bélanger R.E., Marclay F., Berchtold A., Saugy M., Cornuz J., Suris J.C.
ISSN
1469-994X (Electronic)
ISSN-L
1462-2203
Statut éditorial
Publié
Date de publication
2013
Peer-reviewed
Oui
Volume
15
Numéro
11
Pages
1832-1838
Langue
anglais
Notes
Publication types: Journal Article
Résumé
INTRODUCTION: To determine if mulling, the process of adding tobacco to cannabis for its consumption, exposes young cannabis users to significant levels of nicotine.
METHODS: This observational study performed in 2009-2010 among Swiss youths aged 16-25 years involved the completion of a self-administrated questionnaire and the collection of a urine sample on the same day. Measures of urinary cotinine were blindly performed using liquid chromatography coupled-mass spectrometry. A total of 197 eligible participants were divided in 3 groups based on their consumption profile in the past 5 days: 70 abstainers (ABS) not having used cigarettes or cannabis, 57 cannabis users adding tobacco to the cannabis they smoke (MUL) but not having smoked cigarettes, and 70 cigarette smokers (CIG) not having smoked cannabis.
RESULTS: Exposure to nicotine was at its lowest among ABS with a mean (SE) cotinine level of 3.2 (1.4) ng/ml compared, respectively, with 214.6 (43.8) and 397.9 (57.4) for MUL and CIG (p < .001). While consumption profile appeared as the only significant factor of influence when examining nicotine exposure from the ABS and MUL participants on multivariate analysis, it did not result in substantial differences among MUL and CIG groups.
CONCLUSIONS: Urinary cotinine levels found among MUL are high enough to indicate a significant exposure to nicotine originating from the mulling process. In line with our results, health professionals should pay attention to mulling as it is likely to influence cannabis and cigarette use as well as the efficacy of cessation interventions.
Pubmed
Web of science
Création de la notice
22/09/2013 19:29
Dernière modification de la notice
20/08/2019 15:19
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