Astrocyte Ca²⁺ signalling: an unexpected complexity.

Détails

Ressource 1Télécharger: BIB_B05989618118.P001.pdf (5571.79 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_B05989618118
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Astrocyte Ca²⁺ signalling: an unexpected complexity.
Périodique
Nature Reviews. Neuroscience
Auteur(s)
Volterra A., Liaudet N., Savtchouk I.
ISSN
1471-0048 (Electronic)
ISSN-L
1471-003X
Statut éditorial
Publié
Date de publication
05/2014
Peer-reviewed
Oui
Volume
15
Numéro
5
Pages
327-335
Langue
anglais
Résumé
Astrocyte Ca(2+) signalling has been proposed to link neuronal information in different spatial-temporal dimensions to achieve a higher level of brain integration. However, some discrepancies in the results of recent studies challenge this view and highlight key insufficiencies in our current understanding. In parallel, new experimental approaches that enable the study of astrocyte physiology at higher spatial-temporal resolution in intact brain preparations are beginning to reveal an unexpected level of compartmentalization and sophistication in astrocytic Ca(2+) dynamics. This newly revealed complexity needs to be attentively considered in order to understand how astrocytes may contribute to brain information processing.
Mots-clé
Animals, Astrocytes/physiology, Astrocytes/ultrastructure, Brain/cytology, Calcium/metabolism, Calcium Signaling/physiology, Humans, Synapses/physiology
Pubmed
Web of science
Open Access
Oui
Création de la notice
08/09/2014 13:04
Dernière modification de la notice
20/08/2019 15:19
Données d'usage