Administration de facteur VII activé recombinant chez une patiente porteuse d'une assistance mécanique ventriculaire gauche [rFVIIa administration in patient with a left ventricular assistance patient]

Details

Serval ID
serval:BIB_AFE8864CC685
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Administration de facteur VII activé recombinant chez une patiente porteuse d'une assistance mécanique ventriculaire gauche [rFVIIa administration in patient with a left ventricular assistance patient]
Journal
Annales francaises d'anesthesie et de reanimation
Author(s)
Tual L., Kirsch M., Servant J.M., Drouet L., Dhonneur G.
ISSN
0750-7658 (Print)
ISSN-L
0750-7658
Publication state
Published
Issued date
01/2006
Peer-reviewed
Oui
Volume
25
Number
1
Pages
29-32
Language
french
Notes
Publication types: Case Reports ; English Abstract ; Journal Article
Publication Status: ppublish
Abstract
We report the case of a left ventricular mechanical assistance (Incor Berlinheart) in a woman that experienced a postoperative non-surgical haemorrhagic complication following a reconstructive pedicled omentoplasty for implanted materials infection. After massive substitutive therapy failure at reducing blood loss and because of an hypovolaemic shock, high dosage (70 microg/kg twice) of recombinant activated factor VII (r-VIIa) was administrated resulting in spectacular cessation of bleeding and haemodynamic restoration. Continuous repeated clinical evaluation, cardiac echography and electronic monitoring of the axial pump device characteristic did not reveal any thromboembolic accident. This observation brings some indirect arguments for safe rFVIIa treatment in this type of pathology with a high thromboembolic risk.
Keywords
Aged, Factor VIIa/therapeutic use, Heart-Assist Devices, Hemorrhage/drug therapy, Humans, Male, Omentum/surgery, Postoperative Complications/drug therapy, Prosthesis-Related Infections/surgery, Recombinant Proteins/therapeutic use, Shock/drug therapy, Thromboembolism/complications
Pubmed
Web of science
Create date
30/03/2019 17:48
Last modification date
20/08/2019 16:19
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