Intra-arterial vasodilators infusion for management of reversible cerebral vasoconstriction syndrome in a 12-year-old girl: A case report.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_AFDEEBEA528D
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Intra-arterial vasodilators infusion for management of reversible cerebral vasoconstriction syndrome in a 12-year-old girl: A case report.
Journal
Frontiers in pediatrics
Author(s)
Rizzati F., Marie G., Chanez V., Ferry T., Natterer J., Longchamp D., Saliou G., Perez M.H.
ISSN
2296-2360 (Print)
ISSN-L
2296-2360
Publication state
Published
Issued date
2023
Peer-reviewed
Oui
Volume
11
Pages
1042509
Language
english
Notes
Publication types: Case Reports
Publication Status: epublish
Abstract
Reversible cerebral vasoconstriction syndrome (RCVS) is a vascular disease characterized by diffuse transient vasoconstriction and vasodilatation of the cerebral arteries. It is commonly associated with recurrent severe acute headaches with or without focal neurological deficits due to hemorrhages, infarcts, and even posterior reversible encephalopathy syndrome. The optimal management of acute neurologic deficits caused by RCVS is still uncertain. Calcium channel blockers (CCBs) such as nimodipine or verapamil have been reported to be effective in adult series. Intra-arterial injection of nimodipine, verapamil, and milrinone has recently been demonstrated to be safe and effective for treating severe segmental vasoconstriction in adults. CCBs are the most used treatment in the available pediatric literature. Intra-arterial vasodilators have been reported in some rare pediatric reports with more severe diseases, but their utility is still under investigation. We report a case of a 12-year-old girl who underwent a severe course of RCVS complicated by multiple cerebral infarcts, treated by several sessions of intra-arterial vasodilators infusion.
Keywords
case report, children, headache, pediatric intensive care unit, reversible cerebral vasoconstriction syndrome, vessel wall MRI
Pubmed
Web of science
Open Access
Yes
Create date
24/03/2023 11:37
Last modification date
03/04/2023 5:54
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