Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP).

Détails

ID Serval
serval:BIB_AF18E88AE939
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP).
Périodique
International journal of cardiology
Auteur(s)
Keeble T.R., Karamasis G.V., Rothman M.T., Ricksten S.E., Ferrari M., Hullin R., Scherstén F., Reitan O., Kirking S.T., Cleland JGF, Smith E.J.
ISSN
1874-1754 (Electronic)
ISSN-L
0167-5273
Statut éditorial
Publié
Date de publication
15/01/2019
Peer-reviewed
Oui
Volume
275
Pages
53-58
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study ; Observational Study
Publication Status: ppublish
Résumé
Worsening heart failure complicated by congestion, hypotension, and renal dysfunction is difficult to manage, increasingly common and predicts a poor outcome. Novel therapies are required to facilitate diuresis and implementation of disease-modifying interventions in preparation for hospital discharge. Accordingly, we investigated the haemodynamic and renal effects of the Reitan Catheter Pump (RCP) percutaneous support device in patients admitted with decompensated heart failure (DHF).
This was a prospective observational study of 20 patients admitted with DHF, ejection fraction < 30%, and Cardiac index (CI) < 2.1 L/min/m <sup>2</sup> in need of inotropic/mechanical support.
Patients underwent RCP support for a mean of 18.3 (±6.3) hours. The RCP increased CI from 1.84 L/min/m <sup>2</sup> (±0.27), to 2.41 L/min/m <sup>2</sup> (±0.45, p = 0.04), increased urine output (71 mL/h (±65) to 227 ml/h (±179) (p = 0.006) with a concomitant reduction in serum creatinine (188 μmol/L (±87) to 161 μmol/L (±78) (p = 0.0007). There were no clinically significant haemolysis, vascular injury, or thrombo-embolic complications.
For patients admitted with DHF, the RCP improves cardiac index, diuresis and renal function without causing important complications.
Mots-clé
Aged, Cardiac Catheterization/methods, Creatinine/blood, Diuresis/physiology, Equipment Design, Female, Follow-Up Studies, Glomerular Filtration Rate/physiology, Heart Failure/complications, Heart Failure/physiopathology, Heart Failure/therapy, Heart-Assist Devices, Humans, Kidney/physiopathology, Male, Prospective Studies, Renal Insufficiency/etiology, Renal Insufficiency/physiopathology, Renal Insufficiency/prevention & control, Stroke Volume/physiology, Ventricular Function, Left/physiology, Cardiac support, Congestion, Decompensated heart failure, Renal dysfunction
Pubmed
Web of science
Création de la notice
05/11/2018 10:27
Dernière modification de la notice
20/08/2019 16:18
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