Brainstem activation specific to migraine headache.

Details

Serval ID
serval:BIB_AE09B84F1529
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Title
Brainstem activation specific to migraine headache.
Journal
Lancet
Author(s)
Bahra A., Matharu M.S., Buchel C., Frackowiak R.S., Goadsby P.J.
ISSN
0140-6736 (Print)
ISSN-L
0140-6736
Publication state
Published
Issued date
2001
Volume
357
Number
9261
Pages
1016-1017
Language
english
Notes
Publication types: Case Reports ; LetterPublication Status: ppublish
Abstract
Findings from functional imaging studies have shown activation of the brainstem during migraine without aura (MWOA) and activation of the hypothalamus during cluster headache. We assessed a patient with cluster headache and migraine by positron emission tomography during an active cluster headache after he had taken 1.2 glyceryl trinitate. The patient developed a typical MWOA, during which we saw activation in the dorsal rostral brainstem. There was no activation in the region of the hypothalamus. Our findings provide evidence that migraine involves the brainstem, and show several areas involved in cluster headaches. Our data show the potential for objective distinction between primary headache syndromes with functional imaging, in disorders hitherto distinguished on clinical grounds.
Keywords
Adult, Brain Stem/physiopathology, Brain Stem/radionuclide imaging, Cluster Headache/physiopathology, Cluster Headache/radionuclide imaging, Humans, Male, Migraine without Aura/physiopathology, Migraine without Aura/radionuclide imaging, Nitroglycerin/diagnostic use, Tomography, Emission-Computed
Pubmed
Web of science
Create date
12/09/2011 20:36
Last modification date
20/08/2019 16:17
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