Electronic Dura Mater Meddling in the Central Nervous System.

Details

Serval ID
serval:BIB_ADA7A5E4E941
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Electronic Dura Mater Meddling in the Central Nervous System.
Journal
JAMA neurology
Author(s)
Bloch J., Lacour S.P., Courtine G.
ISSN
2168-6157 (Electronic)
ISSN-L
2168-6149
Publication state
Published
Issued date
01/04/2017
Peer-reviewed
Oui
Volume
74
Number
4
Pages
470-475
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
A growing number of neurologic treatments rely on neural implants capable of delivering electrical and chemical stimulation to targeted regions of the central nervous system for extended periods.
To assess the potential of a novel class of multimodal neural implants, termed electronic dura mater or e-dura, to fulfill this need.
Results from preclinical applications of e-dura implants and clinical evidence.
The silicone-based implant e-dura embeds interconnects, electrodes, and chemotrodes that are entirely stretchable. These unique mechanical properties allow e-dura to conform to the circumvolutions of the brain and spinal cord without damaging neural tissues or triggering foreign body reactions.
Although challenges lie ahead to reach clinical fruition, the unique mechanical properties and integrated modalities of e-dura provide future opportunities to treat or alleviate neurologic deficits.

Pubmed
Web of science
Create date
28/04/2017 11:14
Last modification date
20/08/2019 15:17
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