European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

Details

Serval ID
serval:BIB_AD5160136E47
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease
Journal
European Journal of Nuclear Medicine
Author(s)
Maisey  M. N., Lowry  A., Bischof-Delaloye  A., Fridrich  R., Inglese  E., Khalil  M. N., van der Schoot  J. B.
ISSN
0340-6997 (Print)
Publication state
Published
Issued date
1990
Volume
16
Number
12
Pages
869-72
Notes
Clinical Trial
Comparative Study
Controlled Clinical Trial
Journal Article
Multicenter Study
Abstract
Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses.
Keywords
Contrast Media Coronary Disease/*radionuclide imaging Europe Female Heart/*radionuclide imaging Humans Male Middle Aged Nitriles/*diagnostic use Organotechnetium Compounds/*diagnostic use Sensitivity and Specificity Technetium Tc 99m Sestamibi Thallium Radioisotopes/*diagnostic use
Pubmed
Web of science
Create date
25/01/2008 11:22
Last modification date
20/08/2019 15:17
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